ALDOA(aldolase A, fructose-bisphosphate) 转至新版数据库

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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16p11.2
基因染色体位置图

The protein encoded by this gene, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10. [provided by RefSeq, Aug 2011]

[中文简述(自动翻译):]  由该基因编码的蛋白质,醛缩酶A(醛缩酶),是催化果糖-1,6-双磷酸,以甘油醛-3-磷酸和二羟基丙酮磷酸的可逆转换糖酵解酶。三醛缩酶同工酶(A,B和C)中,由三个不同的基因编码,在开发过程中差异表达。醛缩酶A在发育中的胚胎中发现,并且在成年肌肉甚至更大量的产生。醛缩酶A表达在成年肝,肾,肠和类似醛缩酶在脑和其他神经组织C水平压制。醛缩酶A缺乏症已与肌病和溶血性贫血有关。选择性剪接,并在多个转录变异体替代的启动子的使用的结果。相关假已经确定在[由RefSeq的,2011年8月提供]染色体3和10

ALDOA基因的碱基序列:[NCBI]
ALDOA基因的碱基突变:           显示全部snp
rs11135       rs12831       rs1061406       rs1061993       rs1062217       rs1062379       rs1138624       rs2071389       rs2071390       rs3098412       rs3098413       rs3098414       rs3098416       rs3098417       rs3098418       rs3112553       rs3112555       rs3112557       rs3112558       rs3134619       rs3134620       rs3134621       rs3134622       rs3134625       rs3134626       rs3134627       rs3169548       rs3207373       rs3751869       rs4788219       rs4788220       rs7189140       rs8059574       rs9783783       rs9928448       rs9932193       rs9939774      
rs11553107       rs11553108       rs11553112       rs11553113       rs11860935       rs11867026       rs12933729       rs17842264       rs34244481       rs34344236       rs34429195       rs34855001       rs35411808       rs41280854       rs41280858       rs55864320       rs57975226       rs58098996       rs58621401       rs60898365       rs71143773       rs71389444       rs73530148       rs74983000       rs75324226       rs75559164       rs75721735       rs76144388       rs76642620       rs76696455       rs76767223       rs77096737       rs77202585       rs77290575       rs77320009       rs77821461       rs77865062       rs78124282       rs78192296       rs78209292       rs78210758       rs78564892       rs79157323       rs79968733       rs111252736       rs111253703       rs112110009       rs112230352       rs112565363       rs112839064       rs113090361       rs113178329       rs113222518       rs113667276       rs113755217       rs113897028       rs114148986       rs114445168       rs114448698       rs115483868       rs116317239       rs116838618       rs116867648       rs116878064       rs117114611       rs118046230       rs137948770       rs138053423       rs138476963       rs138505683       rs138548394       rs138824667       rs139286715       rs139313062       rs139934917       rs139980930       rs140201659       rs140743496       rs140870604       rs141220324       rs141386658       rs141764904       rs141861282       rs142231603       rs142242422       rs142315181       rs142338109       rs142701601       rs142759891       rs142872164       rs142892476       rs142908759       rs142957871       rs142991928       rs143152280       rs143195977       rs143419532       rs143511915       rs143618512       rs144443798       rs144550952       rs144611000       rs144632574       rs144671145       rs144673637       rs144693278       rs144793528       rs145220491       rs145372996       rs145479598       rs145582724       rs145811469       rs146025467       rs146109120       rs146116144       rs146835556       rs146903645       rs146914049       rs146976414       rs147193284       rs147478664       rs147612848       rs147689701       rs147865729       rs147962455       rs148066566       rs148127725       rs148193398       rs148454650       rs148503847       rs148504799       rs148828956       rs148880951       rs149186779       rs149313961       rs149504755       rs149829776       rs150003720       rs150320489       rs150482105       rs150741747       rs150795724       rs151069138       rs151109981       rs180912730       rs180962387       rs181397696       rs181522608       rs181606186       rs181784874       rs182063751       rs182364026       rs182537574       rs182548550       rs182964795       rs182991360       rs183452993       rs183613085       rs183633002       rs183654049       rs184162259       rs184244583       rs184290946       rs184538125       rs184741950       rs185362207       rs185462650       rs185558087       rs185814907       rs186025943       rs186320122       rs186656423       rs186785222       rs186985839       rs187227964       rs187258277       rs187545048       rs187550606       rs188052082       rs188053632       rs188263087       rs188512463       rs188565880       rs188784065       rs188898200       rs189419268       rs189663136       rs189723657       rs190121873       rs190213832       rs190221518       rs190371937       rs190372879       rs190479441       rs190807070       rs190892434       rs191041320       rs191103074       rs191226606       rs191614112       rs191805534       rs191954451       rs192037036       rs192333744       rs192636765       rs192665994       rs193058046       rs193076088       rs199653623       rs199655729       rs199726944       rs199775687       rs199852002       rs199979815       rs200278984       rs200556590       rs200588805       rs200614642       rs200733968       rs200761497       rs201141448       rs201346640       rs201468609       rs201519764       rs201610579       rs201627751       rs201658390       rs201718271       rs201927726       rs202079871       rs367545015       rs367758674       rs368025105       rs368207656       rs368682055       rs368691859       rs368816502       rs369189014       rs369475469       rs369551047       rs369593749       rs369668963       rs369822049       rs370112401       rs370218762       rs370909055       rs371424538       rs371593891       rs371785490       rs371944000       rs371956038       rs372075819       rs372148189       rs372660877       rs372684193       rs372686010       rs372878864       rs373133306       rs373229343       rs373254754       rs373402971       rs373517060       rs373670009       rs373869890       rs374042346       rs374231136       rs375097754       rs375294816       rs375434995       rs375546208       rs375858001       rs375985075       rs376709866       rs376845083       rs376849543       rs376951900       rs376977302       rs377025581       rs377030043       rs377623839       rs397799050       rs527778531       rs527885647       rs528099349       rs528189066       rs528228821       rs528386923       rs528778063       rs528913350       rs529816416       rs529854683       rs529854716       rs529860854       rs529976977       rs530089317       rs530326049       rs530521562       rs530630307       rs530821993       rs530899627       rs530946431       rs531033350       rs531110255       rs531405962       rs531820255       rs531858818       rs531993650       rs532110349       rs532330394       rs532473202       rs532744427       rs533450499       rs533708456       rs533835981       rs534019558       rs534058587       rs534264493       rs534465340       rs534606487       rs534767867       rs534946665       rs535074983       rs535100528       rs535136285       rs535217608       rs535503728       rs535505848       rs535837081       rs536037630       rs536039533       rs536199484       rs536229013       rs536306535       rs536394996       rs536465863       rs536670780       rs537074077       rs537186980       rs537375240       rs537416474       rs537504106       rs537877443       rs537906999       rs537989672       rs537993199       rs538205256       rs538492279       rs538577451       rs538807329       rs538850202       rs538925562       rs538961928       rs539073363       rs539174924       rs539661228       rs539833998       rs540162856       rs540210370       rs540246873       rs540258225       rs540284605       rs540367660       rs540476753       rs540564690       rs541327665       rs541443216       rs541491890       rs541579725       rs541579904       rs541638034       rs541763337       rs541891948       rs542426845       rs542638710       rs542788202       rs542882908       rs542921450       rs542989651       rs543153295       rs543745741       rs543849456       rs543906637       rs543940709       rs543994647       rs544024045       rs544104218       rs544179066       rs544466443       rs544553472       rs544777367       rs545165122       rs545350470       rs545566515       rs545876148       rs546253056       rs546577561       rs546768106       rs546927256       rs546976628       rs547789907       rs547961701       rs548074747       rs548110949       rs548228494       rs548243129       rs548345281       rs548757314       rs548980384       rs549102680       rs549146709       rs549264768       rs549290445       rs549303290       rs549338901       rs549397062       rs549434187       rs549471082       rs549658640       rs549901379       rs550013749       rs550180856       rs550571992       rs550680791       rs550747579       rs550858469       rs550915077       rs551031437       rs551085792       rs551354058       rs551464019       rs551680431       rs551939309       rs552024334       rs552061511       rs552402118       rs552539779       rs552929357       rs553240839       rs553340106       rs553388837       rs553675482       rs554192014       rs554380852       rs554392023       rs554432237       rs554533605       rs554570574       rs554645917       rs554730607       rs554856640       rs555044991       rs555047213       rs555085776       rs555376001       rs555598778       rs555603706       rs555628582       rs555731850       rs555768701       rs555988454       rs556547348       rs556709537       rs556908672       rs557226507       rs557278844       rs557439036       rs557625278       rs557786865       rs558220517       rs558364749       rs558389815       rs558422830       rs558565333       rs558635101       rs558845813       rs559067753       rs559623784       rs559744763       rs559753731       rs559778091       rs559877885       rs559907909       rs560360519       rs560829871       rs560915717       rs560979180       rs561096547       rs561108196       rs561258448       rs561867079       rs561946966       rs562179070       rs562373415       rs562390740       rs562495709       rs562655563       rs562656501       rs562771487       rs562931751       rs562968780       rs563388888       rs563412698       rs563447533       rs563664276       rs563777048       rs563984132       rs564264849       rs564441394       rs564772589       rs564825198       rs564856300       rs564974715       rs565013143       rs565257791       rs565305185       rs565421727       rs565509530       rs565677087       rs566225505       rs566248386       rs566360526       rs566611884       rs566612278       rs566755208       rs566822802       rs567300995       rs567320668       rs567480076       rs567692693       rs567803172       rs567878971       rs568400618       rs568745926       rs568910442       rs568997432       rs569148073       rs569310637       rs569354275       rs569708817       rs570185207       rs570272813       rs570385246       rs570432603       rs570468250       rs570629665       rs570781314       rs570868786       rs570954544       rs571039346       rs571323990       rs571465340       rs571552085       rs571695427       rs571792449       rs571988529       rs572244552       rs572924734       rs572933721       rs572970341       rs573166112       rs573197231       rs573479181       rs573836554       rs573853280       rs574106376       rs574219676       rs574359378       rs574908882       rs575060506       rs575098681       rs575447672       rs575627151       rs575635959       rs576122083       rs576186402       rs576234467       rs576367450       rs576438817       rs576724231       rs576738017       rs576765359       rs576869912       rs577102775       rs577338176       rs577867689       rs577925837       rs577953210       rs578046431       rs745449029       rs745518404       rs745528292       rs746068220       rs746119840       rs746301013       rs746350079       rs746388986       rs746453321       rs746684326       rs746865548       rs746955557       rs747160542       rs747173726       rs747330187       rs747443135       rs747482925       rs747490108       rs747670144       rs747788394       rs747888913       rs748069154       rs748293364       rs748329393       rs748384981       rs748584064       rs748606517       rs748620627       rs748819122       rs748910173       rs748925881       rs749215165       rs749443540       rs749536126       rs749551179       rs749774016       rs750132032       rs750157849       rs750388752       rs750622363       rs750630916       rs750880048       rs750912887       rs750927739       rs750976538       rs751111719       rs751275868       rs751467136       rs751539995       rs751632844       rs751804439       rs752128129       rs752184548       rs752195839       rs752431778       rs752432028       rs752478544       rs752587498       rs752601988       rs752764982       rs752890295       rs753278862       rs753301798       rs753336912       rs753571848       rs753723817       rs753738038       rs753739488       rs753928604       rs754078010       rs754143271       rs754370062       rs754372047       rs754442562       rs754601084       rs754771698       rs754806943       rs754905488       rs755235804       rs755870797       rs755913779       rs755937471       rs756024464       rs756568720       rs756568844       rs756621723       rs756734032       rs756789043       rs756916914       rs757047929       rs757070186       rs757124451       rs757343704       rs757708727       rs757710745       rs757739728       rs757847386       rs758000649       rs758280973       rs758285007       rs758454547       rs758491170       rs758499704       rs758552797       rs758724483       rs758837447       rs759070394       rs759139411       rs759238234       rs759371645       rs759406539       rs759432221       rs759520049       rs759561783       rs759684459       rs759758697       rs759847191       rs759944428       rs760090607       rs760143922       rs760253906       rs760287676       rs760307214       rs760489629       rs760550827       rs760700451       rs760807537       rs760894068       rs760900489       rs760980476       rs761178874       rs761469180       rs761558801       rs761705909       rs761836264       rs761952634       rs761982199       rs762219882       rs762292824       rs762386905       rs762473834       rs762591392       rs762685202       rs762779941       rs762797482       rs762881835       rs763131403       rs763299410       rs763478106       rs763532944       rs763665203       rs763665256       rs763716015       rs763806503       rs763894241       rs763974400       rs764063310       rs764176104       rs764211748       rs764289761       rs764408786       rs764440580       rs764462408       rs764633128       rs764960141       rs764984222       rs765047249       rs765244415       rs765436514       rs765730475       rs765795855       rs765883841       rs766193896       rs766537404       rs766537451       rs766590264       rs766734350       rs766766406       rs766907546       rs766939993       rs766960395       rs767080400       rs767548814       rs767685109       rs767738432       rs767840312       rs767849851       rs767951688       rs768071615       rs768153334       rs768538661       rs768596159       rs768645456       rs768645961       rs768647554       rs768714573       rs768921360       rs769145643       rs769327341       rs769378422       rs769441707       rs769563671       rs769597382       rs769709094       rs769800173       rs769854682       rs769860227       rs769905899       rs769938234       rs770061959       rs770093075       rs770097934       rs770507018       rs770516115       rs770613633       rs770621179       rs770793827       rs770983021       rs771313409       rs771553440       rs771557202       rs771740082       rs771967749       rs772036398       rs772200646       rs772297021       rs772548302       rs772550893       rs772559518       rs772781301       rs772786469       rs772798937       rs772853499       rs772908246       rs773340964       rs773402743       rs773418197       rs773422001       rs773475363       rs773634218       rs773684656       rs773896759       rs773916193       rs773971050       rs773990488       rs774085607       rs774444763       rs774517970       rs774739740       rs774939475       rs775049666       rs775098268       rs775117761       rs775119400       rs775439610       rs775550918       rs775578709       rs775705038       rs776187312       rs776454021       rs776529531       rs776721459       rs776760013       rs776950855       rs776994056       rs777258122       rs777581671       rs777625079       rs777632110       rs777636671       rs777723350       rs777791032       rs778192626       rs778342113       rs778572895       rs778773620       rs778814633       rs779241416       rs779383902       rs779421883       rs779460013       rs779556052       rs779567861       rs779577709       rs779902973       rs779963072       rs779998693       rs780248284       rs780378047       rs780522360       rs780958986       rs781147998       rs781198918       rs781380448       rs781628911       rs781754795      

ALDOA基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
GAGACACTCTACCAGAAGGC
60
CTTGTCTACCTTGATGCCCA
60
TCTCCTTGAATCCACTCGC
60
GTAGTAGCAAGTTCCTGGCA
60
TTTCTCATGAGGAGATTGCCA
59
GGAAGGTGATCCCAGTGAC
59
GGGTCATTAGAGAAGATCGGG
60
GGCTGGTTATAAGGCAGCT
60
CAGAACCTTCCTTCTGCAG
58
GAGACAGTTGAGGCTCTGG
60
CAGATGAGTCCACTGGGAG
59
TCTCATGGAAGAGGATGACAC
59
GTATCTGCCAGCAGAATGG
58
AGAGCCTTGTAGACAGCAG
59
TTTCTCATGAGGAGATTGCCA
60
CAGGAAGGTGATCCCAGTG
60
GTATCTGCCAGCAGAATGG
58
AGAGCCTTGTAGACAGCAG
59
CAGATGAGTCCACTGGGAG
59
TCATGGAAGAGGATGACACC
59
      尚未收录相关数据

ALDOA基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

ALDOA基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0004332
H3BMQ8(UniProtKB)
IEA
GO:0006096
H3BMQ8(UniProtKB)
IEA
GO:0004332
H3BPS8(UniProtKB)
IEA
GO:0006096
H3BPS8(UniProtKB)
IEA
GO:0004332
H3BQN4(UniProtKB)
IEA
GO:0006096
H3BQN4(UniProtKB)
IEA
GO:0004332
H3BR04(UniProtKB)
IEA
GO:0006096
H3BR04(UniProtKB)
IEA
GO:0004332
H3BR68(UniProtKB)
IEA
GO:0006096
H3BR68(UniProtKB)
IEA
GO:0004332
H3BU78(UniProtKB)
IEA
GO:0006096
H3BU78(UniProtKB)
IEA
GO:0004332
H3BUH7(UniProtKB)
IEA
GO:0006096
H3BUH7(UniProtKB)
IEA
GO:0004332
J3KPS3(UniProtKB)
IEA
GO:0006096
J3KPS3(UniProtKB)
IEA
GO:0002576
P04075(UniProtKB)
TAS
GO:0003779
P04075(UniProtKB)
TAS
GO:0004332
P04075(UniProtKB)
IDA
GO:0004332
P04075(UniProtKB)
EXP
GO:0004332
P04075(UniProtKB)
IDA
GO:0005515
P04075(UniProtKB)
IPI
GO:0005515
P04075(UniProtKB)
IPI
GO:0005515
P04075(UniProtKB)
IPI
GO:0005576
P04075(UniProtKB)
TAS
GO:0005615
P04075(UniProtKB)
IDA
GO:0005634
P04075(UniProtKB)
IDA
GO:0005829
P04075(UniProtKB)
TAS
GO:0005829
P04075(UniProtKB)
TAS
GO:0006000
P04075(UniProtKB)
IMP
GO:0006094
P04075(UniProtKB)
TAS
GO:0006096
P04075(UniProtKB)
IMP
GO:0006754
P04075(UniProtKB)
IMP
GO:0006941
P04075(UniProtKB)
IMP
GO:0007015
P04075(UniProtKB)
TAS
GO:0008092
P04075(UniProtKB)
IDA
GO:0008360
P04075(UniProtKB)
IDA
GO:0015629
P04075(UniProtKB)
IDA
GO:0015631
P04075(UniProtKB)
TAS
GO:0016020
P04075(UniProtKB)
IDA
GO:0030388
P04075(UniProtKB)
IDA
GO:0030388
P04075(UniProtKB)
IDA
GO:0031093
P04075(UniProtKB)
TAS
GO:0031430
P04075(UniProtKB)
IEA
GO:0031674
P04075(UniProtKB)
TAS
GO:0042802
P04075(UniProtKB)
TAS
GO:0044822
P04075(UniProtKB)
IDA
GO:0046716
P04075(UniProtKB)
IMP
GO:0051289
P04075(UniProtKB)
ISS
GO:0061621
P04075(UniProtKB)
TAS
GO:0070061
P04075(UniProtKB)
IDA
GO:0070061
P04075(UniProtKB)
IDA
GO:0070062
P04075(UniProtKB)
IDA
GO:0070062
P04075(UniProtKB)
IDA
GO:0070062
P04075(UniProtKB)
IDA
GO:0070062
P04075(UniProtKB)
IDA
GO:0070062
P04075(UniProtKB)
IDA
GO:0070062
P04075(UniProtKB)
IDA
GO:0070062
P04075(UniProtKB)
IDA
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控ALDOA基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Glycogen Storage Disease XII 0.48 3 3 CLINVAR_CTD_human_ORPHANET_UNIPROT
Neoplasm Invasiveness 0.12 1 0 CTD_human
Neoplasm Metastasis 0.12 1 0 CTD_human
Myocardial Ischemia 0.12 1 0 CTD_human
Adenocarcinoma of lung (disorder) 0.12 1 0 CTD_human
Mammary Neoplasms 0.12 1 0 CTD_human
Reperfusion Injury 0.08 1 0 RGD
Endotoxemia 0.08 1 0 RGD
Anemia 0.002367032 1 0 GAD
Autistic Disorder 0.002367032 1 0 GAD
Anemia, Hemolytic 0.000271442 1 0 BeFree
Anemia, Hemolytic, Congenital 0.000271442 1 0 BeFree
Degenerative polyarthritis 0.000271442 1 0 BeFree
Osteosarcoma 0.000271442 1 0 BeFree
Sleep Apnea, Obstructive 0.000271442 1 0 BeFree
Osteosarcoma of bone 0.000271442 1 0 BeFree
Spondylarthropathies 0.000271442 1 0 BeFree
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