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This gene encodes an enzyme that belongs to the aci-reductone dioxygenase family of metal-binding enzymes, which are involved in methionine salvage. This enzyme may regulate mRNA processing in the nucleus, and may carry out different functions depending on its localization. Related pseudogenes have been defined on chromosomes 8 and 20. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
[中文简述(自动翻译):]  这个基因编码属于该ACI-还原酮加氧酶家族的金属结合的酶,这是参与甲硫氨酸打捞的酶。此酶可在细胞核中调节mRNA加工,并可能进行根据其定位不同的功能。相关假已在染色体8和编码不同亚型的多个转录变异体20选择性剪接的结果确定。 [由RefSeq的,2015年4月提供]
ADI1基因(以及对应的蛋白质)的细胞分布位置:
ADI1基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Prostatic Neoplasms | 0.122995792 | 1 | 0 | BeFree_CTD_human_LHGDN |
Tobacco Use Disorder | 0.002367032 | 1 | 0 | GAD |
Malaria | 0.000542884 | 2 | 0 | BeFree |
Rheumatoid Arthritis | 0.000271442 | 1 | 0 | BeFree |
Neoplasm Metastasis | 0.000271442 | 1 | 0 | BeFree |
Sickle Cell Trait | 0.000271442 | 1 | 0 | BeFree |
Nicotinamide adenine dinucleotide coenzyme Q reductase deficiency | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of prostate | 0.000271442 | 1 | 0 | BeFree |
Prostate carcinoma | 0.000271442 | 1 | 0 | BeFree |
ovarian neoplasm | 0.000271442 | 1 | 0 | BeFree |
Chronic Kidney Diseases | 0.000271442 | 1 | 0 | BeFree |
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