ADGRE5(adhesion G protein-coupled receptor E5)

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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19p13.12
基因染色体位置图

This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19. [provided by RefSeq, Jun 2011]

[中文简述(自动翻译):]  这个基因编码粘附G蛋白偶联受体,其介导细胞 - 细胞相互作用的EGF-TM7亚科的成员。这些蛋白质是由自我催化水解裂解成一个大的胞外亚基和七个跨跨膜亚基,其在细胞表面相关联作为受体复合物。所编码的蛋白质可在细胞粘附作用以及白细胞募集,活化和迁移,以及包含多个外EGF样重复其介导结合硫酸软骨素和细胞表面补体调节蛋白CD55。这个基因的表达可能在几种类型的癌症的进展的作用。可变剪接转录物变体具有3至5 EGF样重复已经观察到这种基因编码多种亚型。该基因与19号染色体短臂其他EGF-TM7基因簇被发现[由RefSeq的,2011年6月提供]

ADGRE5基因的碱基序列:[NCBI]
ADGRE5基因的碱基突变:           显示全部snp
rs888875       rs1042850       rs1984821       rs2016259       rs2230748       rs2302092       rs2302093       rs2302094       rs2302995       rs2302996       rs2302997       rs2420550       rs2901191       rs3182286       rs3786656       rs3786657       rs3786658       rs3826759       rs4468742       rs4517893       rs5827226       rs7251607       rs7255389       rs7257784       rs7260110       rs7508244       rs8102011       rs8105300       rs8105798       rs8108408       rs8108409       rs8108638       rs8113679       rs9917014       rs9917022       rs9917042       rs10404878      
rs10407671       rs10409093       rs10409530       rs10410071       rs10410358       rs10410377       rs10411324       rs10412108       rs10416187       rs10418487       rs10419498       rs10421249       rs10421250       rs10424904       rs10425197       rs10426122       rs11544196       rs11667042       rs11879124       rs12609652       rs12610710       rs12610713       rs12971745       rs12973667       rs12974314       rs12974722       rs13344967       rs13346395       rs16979634       rs16979636       rs17273661       rs28366013       rs28433652       rs28505983       rs28533737       rs28548336       rs28668137       rs28672314       rs34025302       rs34265241       rs34782681       rs35133209       rs35363541       rs35405275       rs35452325       rs35624101       rs45442397       rs45466292       rs45539937       rs55640418       rs55965932       rs56162035       rs56943653       rs56960989       rs57168445       rs58233784       rs58411522       rs58499090       rs58570628       rs59179632       rs61310069       rs61733711       rs61733714       rs61735279       rs61735280       rs62122577       rs62122578       rs62122579       rs62122580       rs62122581       rs62122585       rs67023356       rs67173128       rs67334436       rs67426584       rs67810293       rs67934164       rs71164253       rs71164254       rs71164255       rs71164256       rs73515682       rs73515685       rs73515693       rs73515695       rs73515696       rs73515699       rs73517807       rs73517817       rs73517819       rs73517821       rs73924173       rs73924174       rs73924180       rs73924182       rs74183092       rs74183093       rs74468665       rs74602779       rs74664234       rs74937637       rs75181453       rs75335664       rs75381848       rs75739583       rs75859427       rs75902260       rs75998814       rs76151966       rs76322505       rs76778607       rs76816060       rs77414777       rs78702495       rs78745590       rs78841685       rs79133932       rs79254060       rs79768657       rs79967411       rs111243284       rs111331332       rs111384816       rs111405918       rs111532094       rs111576526       rs111613337       rs111615417       rs111717059       rs111896493       rs111906748       rs112093922       rs112165986       rs112204503       rs112205992       rs112255397       rs112285894       rs112343612       rs112374262       rs112543109       rs112567286       rs112615933       rs112648788       rs112659398       rs112772091       rs112824469       rs112862274       rs112992675       rs113047204       rs113088795       rs113164063       rs113243506       rs113275479       rs113368360       rs113398206       rs113423501       rs113472163       rs113482271       rs113696299       rs113856565       rs113937587       rs113962416       rs113992688       rs114278480       rs114595785       rs114600225       rs114698530       rs114770399       rs114778334       rs114961400       rs115061086       rs115063869       rs115296260       rs115358023       rs115359588       rs115404220       rs115471402       rs115537324       rs115573999       rs115661607       rs116385220       rs116411115       rs116612913       rs116706231       rs116828040       rs117430893       rs117878245       rs137977160       rs138148764       rs138198401       rs138222469       rs138240261       rs138351596       rs138463826       rs138575904       rs138614688       rs138625969       rs138661222       rs138722877       rs138925603       rs138926065       rs138968912       rs139113505       rs139399323       rs139472472       rs139539813       rs139618356       rs139622037       rs139791047       rs140048136       rs140068607       rs140117277       rs140171819       rs140316565       rs140445520       rs140629853       rs140685428       rs140836731       rs140877477       rs141106904       rs141162124       rs141170739       rs141326187       rs141404743       rs141443086       rs141473257       rs141506627       rs141561119       rs141563774       rs141605989       rs141615530       rs141626286       rs141641151       rs141666295       rs141772909       rs141858701       rs141960162       rs142124620       rs142264590       rs142485244       rs142534163       rs142680774       rs142898808       rs142952517       rs143017063       rs143056436       rs143334505       rs143487927       rs143592124       rs143619017       rs143651564       rs143720622       rs143754653       rs143780548       rs143859763       rs144034322       rs144095743       rs144399802       rs144439372       rs144446999       rs144477405       rs144511706       rs144681851       rs144727374       rs144818578       rs144852238       rs145120962       rs145137370       rs145167749       rs145308566       rs145384329       rs145704663       rs145711946       rs145772648       rs145838612       rs145955187       rs145974030       rs146060779       rs146163766       rs146182200       rs146609992       rs146766182       rs146877232       rs146888178       rs146927412       rs147013936       rs147029913       rs147332086       rs147401645       rs147418346       rs147444058       rs147526472       rs147788187       rs147816079       rs147913221       rs147982489       rs148014551       rs148104179       rs148390321       rs148422944       rs148434845       rs148476326       rs148539909       rs148589157       rs148670611       rs148721033       rs148941728       rs148968275       rs149215083       rs149296823       rs149466269       rs149467595       rs149485721       rs149607954       rs149784248       rs149838230       rs149873493       rs149960145       rs149991001       rs150041019       rs150091194       rs150102867       rs150156465       rs150335785       rs150566715       rs150593511       rs150649671       rs150665764       rs150839099       rs150981464       rs151333245       rs180781417       rs180823461       rs180829783       rs181112972       rs181125128       rs181242800       rs181310055       rs181333925       rs181414934       rs181595668       rs181741221       rs181746082       rs181930040       rs182173820       rs182204247       rs182216949       rs182242153       rs182476199       rs182737404       rs182751255       rs182764319       rs182811826       rs182827184       rs183002823       rs183009793       rs183089525       rs183348706       rs183595680       rs183831599       rs183956993       rs183969891       rs184020582       rs184123248       rs184168312       rs184297779       rs184454667       rs184472936       rs184496063       rs184929406       rs184946131       rs184955799       rs185027824       rs185187590       rs185199297       rs185392747       rs185599975       rs185672819       rs185676012       rs185833329       rs185972807       rs186208033       rs186212814       rs186543850       rs186624045       rs186834796       rs186859665       rs186906399       rs186919191       rs187205235       rs187233050       rs187343212       rs187432313       rs187717930       rs187725139       rs187727684       rs187745951       rs188155735       rs188166969       rs188687413       rs188702314       rs188739994       rs189049663       rs189246054       rs189370854       rs189388782       rs189503937       rs189547249       rs189623687       rs189624503       rs189760239       rs189762995       rs189885418       rs190029462       rs190097664       rs190186927       rs190334896       rs190437845       rs190565326       rs190662237       rs190750970       rs190831604       rs190995220       rs191046751       rs191071488       rs191130179       rs191473484       rs191490532       rs191631128       rs191864781       rs191910050       rs192051710       rs192074812       rs192128276       rs192152296       rs192289957       rs192430912       rs192511957       rs192608793       rs192615834       rs192628739       rs192683184       rs192768866       rs192852660       rs192968210       rs192973054       rs193129568       rs193286048       rs199544696       rs199578879       rs199620684       rs199718078       rs199755477       rs199774805       rs199855202       rs199941263       rs199986348       rs200058302       rs200099558       rs200115962       rs200267041       rs200330014       rs200345251       rs200443799       rs200457196       rs200463471       rs200493021       rs200548219       rs200664433       rs200692235       rs200832368       rs200893801       rs200898011       rs200963785       rs201012165       rs201012570       rs201051797       rs201125993       rs201139435       rs201175207       rs201248382       rs201252978       rs201260178       rs201291607       rs201356058       rs201468640       rs201475764       rs201511778       rs201593144       rs201677053       rs201730212       rs201730859       rs201767140       rs201775477       rs201881310       rs201911500       rs201988573       rs202050948       rs202091781       rs202099283       rs202133027       rs367560368       rs367579729       rs367664964       rs367700672       rs367751456       rs367758297       rs367810226       rs367937699       rs367984696       rs367986615       rs368052862       rs368193346       rs368394945       rs368591354       rs368601402       rs368642237       rs368823768       rs368847648       rs368847983       rs368992684       rs369039689       rs369154311       rs369186824       rs369212430       rs369349812       rs369475079       rs369489220       rs369581042       rs369602896       rs369617596       rs369644066       rs369836030       rs369840270       rs369866245       rs369873330       rs369879233       rs370019447       rs370055411       rs370075764       rs370104930       rs370154853       rs370160434       rs370176467       rs370461653       rs370635077       rs370638550       rs370682934       rs370976136       rs370979328       rs370989320       rs371030779       rs371060993       rs371134981       rs371185748       rs371403378       rs371404297       rs371430739       rs371435199       rs371441293       rs371476424       rs371611881       rs371612036       rs371640173       rs371695389       rs371830952       rs371916473       rs372021393       rs372048160       rs372126773       rs372142422       rs372177708       rs372215749       rs372231585       rs372235855       rs372467792       rs372469384       rs372509996       rs372589064       rs372680454       rs372696186       rs372702707       rs372715209       rs372724761       rs372828026       rs372889912       rs372890121       rs372902968       rs373067809       rs373088351       rs373259044       rs373515389       rs373546791       rs373623468       rs373633503       rs373669459       rs373788401       rs373800132       rs374215660       rs374281399       rs374358158       rs374359701       rs374452617       rs374483356       rs374486556       rs374521557       rs374525465       rs374583489       rs374621992       rs374718424       rs374788142       rs374807034       rs374862599       rs374936199       rs374957908       rs375130099       rs375322648       rs375453281       rs375502494       rs375560787       rs375567054       rs375585368       rs375626703       rs375634012       rs375635650       rs375695239       rs375782489       rs375843291       rs375863625       rs375872269       rs375988849       rs375991646       rs376341660       rs376379956       rs376388702       rs376478700       rs376485958       rs376501705       rs376589934       rs376677729       rs376707519       rs376709007       rs376738555       rs376798007       rs376851668       rs376892799       rs376980277       rs377049610       rs377242536       rs377256419       rs377266346       rs377486765       rs377622562       rs377627126       rs377711177       rs397859135       rs398039160       rs527288068       rs527297030       rs527355394       rs527426396       rs527427790       rs527479033       rs527553089       rs527621682       rs527745246       rs527881857       rs527960826       rs528022331       rs528376318       rs528461807       rs528466481       rs528546414       rs528555528       rs528594366       rs528653932       rs528717347       rs528778715       rs528906484       rs529027527       rs529229998       rs529233392       rs529281017       rs529291130       rs529500310       rs529621293       rs529769014       rs530028582       rs530163471       rs530181647       rs530441056       rs530532981       rs530574587       rs530579534       rs530679639       rs530817007       rs531063489       rs531217666       rs531332193       rs531346292       rs531385483       rs531524506       rs531875134       rs531931453       rs531931567       rs532069335       rs532081899       rs532296030       rs532449667       rs532686091       rs532751957       rs532799816       rs532842484       rs532889208       rs532897217       rs532901763       rs533158443       rs533229316       rs533230344       rs533436649       rs533853482       rs533917495       rs534111626       rs534116041       rs534119168       rs534255879       rs534331259       rs534335358       rs534527209       rs534645020       rs534689441       rs534693341       rs534896117       rs534962403       rs535030208       rs535438698       rs535506585       rs535530363       rs535571645       rs535626617       rs535783064       rs535822037       rs535831728       rs535866523       rs535867869       rs535897631       rs536134311       rs536315094       rs536449254       rs536641378       rs536858371       rs537004630       rs537122672       rs537182796       rs537202537       rs537262542       rs537390059       rs537837589       rs538015012       rs538058848       rs538182718       rs538391653       rs538402110       rs538463854       rs538504433       rs538564533       rs538740646       rs539038856       rs539041517       rs539308791       rs539308872       rs539388387       rs539405076       rs539525134       rs539653082       rs539717447       rs539719626       rs539780640       rs539792040       rs539797015       rs540069379       rs540110369       rs540225892       rs540247637       rs540299152       rs540357515       rs540389924       rs540455835       rs540493462       rs540539124       rs540628755       rs540650975       rs540759823       rs540893617       rs540893684       rs540955028       rs540985375       rs541048649       rs541462676       rs541751483       rs541846761       rs541871046       rs541923554       rs541935943       rs542070413       rs542085337       rs542094058       rs542313874       rs542401060       rs542458113       rs542491672       rs543167147       rs543169449       rs543193914       rs543267653       rs543297241       rs543428816       rs543480274       rs543750396       rs543937250       rs544001974       rs544028365       rs544222222       rs544290472       rs544382926       rs544442472       rs544551492       rs544604794       rs544605145       rs544705782       rs544738378       rs544747231       rs544766122       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rs767721301       rs767761148       rs767776449       rs767811429       rs767863811       rs767882697       rs767890327       rs767899339       rs767933713       rs767944545       rs768001496       rs768030683       rs768097109       rs768098128       rs768234238       rs768282153       rs768300363       rs768330923       rs768342415       rs768393463       rs768411293       rs768449142       rs768450284       rs768683250       rs768684495       rs768739910       rs768759629       rs768790458       rs768840803       rs768847602       rs768917949       rs769103586       rs769156862       rs769239697       rs769255612       rs769304284       rs769329719       rs769484947       rs769488464       rs769576560       rs769608568       rs769634013       rs769661789       rs769799472       rs769830889       rs769847704       rs769883900       rs769972890       rs770014400       rs770027786       rs770034979       rs770104603       rs770297845       rs770357759       rs770364806       rs770383003       rs770511592       rs770592573       rs770610284       rs770711965       rs770722528       rs770768759       rs770820104       rs770940150       rs770981935       rs770990137       rs771102173       rs771117966       rs771146818       rs771227562       rs771266840       rs771352449       rs771510225       rs771532490       rs771739352       rs771926741       rs771931831       rs772068369       rs772097638       rs772102515       rs772156258       rs772157605       rs772179354       rs772249220       rs772327908       rs772345607       rs772380970       rs772418563       rs772503801       rs772603161       rs772678025       rs772681384       rs772693003       rs772694731       rs772734859       rs772782622       rs772818941       rs772933924       rs772974458       rs772992066       rs773149157       rs773158788       rs773209531       rs773244080       rs773293918       rs773308539       rs773386653       rs773430355       rs773532840       rs773574215       rs773694479       rs773727277       rs773778616       rs773784495       rs773786244       rs773899637       rs774033757       rs774058089       rs774155102       rs774293595       rs774449015       rs774474296       rs774479929       rs774561390       rs774568962       rs774580391       rs774624664       rs774656698       rs774670795       rs774726278       rs774768569       rs774780759       rs774912268       rs774955519       rs774961075       rs775035938       rs775060920       rs775089878       rs775155130       rs775160830       rs775192070       rs775216058       rs775345308       rs775414000       rs775429595       rs775499930       rs775503140       rs775651358       rs775715718       rs775734587       rs775811895       rs775811992       rs775824559       rs775891310       rs775974821       rs776020562       rs776053657       rs776204007       rs776277781       rs776284450       rs776301387       rs776478430       rs776571819       rs776579920       rs776662502       rs776767113       rs776809700       rs776947382       rs776974784       rs777093304       rs777131793       rs777230363       rs777234691       rs777293984       rs777301199       rs777318452       rs777421581       rs777641117       rs777660200       rs777689888       rs777777769       rs777823572       rs777939112       rs777962770       rs777978127       rs778057042       rs778091876       rs778190346       rs778288603       rs778322870       rs778346431       rs778383060       rs778432565       rs778493441       rs778564424       rs778624203       rs778651208       rs778656409       rs778679762       rs778693810       rs778697801       rs778751632       rs778850791       rs778855090       rs778920084       rs778922935       rs779033967       rs779201312       rs779206357       rs779222682       rs779234640       rs779343827       rs779473458       rs779490100       rs779507230       rs779578098       rs779594650       rs779808294       rs779841515       rs779947075       rs779984168       rs779999944       rs780035410       rs780037414       rs780100765       rs780179262       rs780253419       rs780338842       rs780399983       rs780435216       rs780454808       rs780454884       rs780493480       rs780564222       rs780578398       rs780589696       rs780720952       rs780781816       rs780869042       rs780999096       rs781010964       rs781042195       rs781059700       rs781089508       rs781103729       rs781112760       rs781289939       rs781309744       rs781353076       rs781364735       rs781476679       rs781566186       rs781640436       rs781680090       rs781702598       rs781734469       rs796673849       rs869111874      

ADGRE5基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
GTCTGTGAAGACGCTTTCC
59
TTACCTGGATGGTGACCTC
58
ATGACTTTCTCCACCTGGAC
60
GAAGAATCGGGAAAGCGTC
59
CCTGACCTCAGGTGATCTG
59
TACAGAAAGTGGTGCTCCA
59
GACTTTCTCCACCTGGACC
60
GAAGAATCGGGAAAGCGTC
59
CCTGACCTCAGGTGATCTG
59
TACAGAAAGTGGTGCTCCAG
60
ACACCGTGGGTTCATACAG
60
GGAGAAAGTCATATCTTCACAGAC
59
CCTCAGAACTCCTCGTGTG
60
CACACTCGTTGATGTCGTC
59
TGACTTTCTCCACCTGGAC
59
GAAGAATCGGGAAAGCGTC
59
ACACCGTGGGTTCATACAG
60
GAGAAAGTCATATCTTCACAGACAG
59
CCTCAGAACTCCTCGTGTG
60
CACTCGTTGATGTCGTCAC
59
      尚未收录相关数据

ADGRE5基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

ADGRE5基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0004930
K7EKV5(UniProtKB)
IEA
GO:0005509
K7EKV5(UniProtKB)
IEA
GO:0007186
K7EKV5(UniProtKB)
IEA
GO:0016020
K7EKV5(UniProtKB)
IEA
GO:0004930
K7EPE8(UniProtKB)
IEA
GO:0005509
K7EPE8(UniProtKB)
IEA
GO:0007186
K7EPE8(UniProtKB)
IEA
GO:0016020
K7EPE8(UniProtKB)
IEA
GO:0004930
K7EPP8(UniProtKB)
IEA
GO:0005509
K7EPP8(UniProtKB)
IEA
GO:0007186
K7EPP8(UniProtKB)
IEA
GO:0016020
K7EPP8(UniProtKB)
IEA
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控ADGRE5基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
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