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This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  这个基因编码六个不同的肌动蛋白的蛋白质之一。肌动蛋白是高度保守的是参与细胞运动,结构和完整性的蛋白。此肌动蛋白是收缩装置的主要组成部分和两个非肌肉细胞骨架肌动蛋白中的一个。 [由RefSeq的,2008年7月提供]
ACTB基因(以及对应的蛋白质)的细胞分布位置:
ACTB基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Juvenile-onset dystonia | 0.48 | 1 | 1 | CLINVAR_CTD_human_ORPHANET_UNIPROT |
| Iris Coloboma with Ptosis, Hypertelorism, and Mental Retardation | 0.24 | 1 | 16 | CLINVAR_UNIPROT |
| Dystonia | 0.122995792 | 1 | 0 | BeFree_CTD_human_LHGDN |
| Liver carcinoma | 0.121628651 | 8 | 0 | BeFree_CTD_human |
| Anoxia | 0.12 | 1 | 0 | CTD_human |
| Congenital ocular coloboma (disorder) | 0.12 | 1 | 0 | CTD_human |
| Dysostoses | 0.12 | 1 | 0 | CTD_human |
| Esophageal Neoplasms | 0.12 | 1 | 0 | CTD_human |
| Sensorineural Hearing Loss (disorder) | 0.12 | 1 | 0 | CTD_human |
| Lung Neoplasms | 0.12 | 1 | 0 | CTD_human |
| Animal Mammary Neoplasms | 0.12 | 1 | 0 | CTD_human |
| Mammary Neoplasms, Experimental | 0.12 | 1 | 0 | CTD_human |
| Neoplasm Invasiveness | 0.12 | 1 | 0 | CTD_human |
| Degenerative polyarthritis | 0.12 | 1 | 0 | CTD_human |
| Myocardial Ischemia | 0.12 | 1 | 0 | CTD_human |
| Craniofacial Abnormalities | 0.12 | 1 | 0 | CTD_human |
| Congenital neurologic anomalies | 0.12 | 1 | 0 | CTD_human |
| Febrile Convulsions | 0.08 | 1 | 0 | RGD |
| Epilepsy, Temporal Lobe | 0.08 | 1 | 0 | RGD |
| Drug-Induced Liver Injury | 0.08 | 1 | 0 | RGD |
| Malignant neoplasm of breast | 0.003724241 | 6 | 0 | BeFree_GAD |
| Colorectal Carcinoma | 0.001628651 | 6 | 0 | BeFree |
| HIV Infections | 0.001628651 | 6 | 0 | BeFree |
| Prostate carcinoma | 0.001628651 | 6 | 0 | BeFree |
| Down Syndrome | 0.001357209 | 5 | 0 | BeFree |
| Malignant neoplasm of stomach | 0.001357209 | 5 | 0 | BeFree |
| Malignant neoplasm of prostate | 0.001357209 | 5 | 0 | BeFree |
| Breast Carcinoma | 0.001357209 | 5 | 0 | BeFree |
| Stomach Carcinoma | 0.001357209 | 5 | 0 | BeFree |
| Colorectal Cancer | 0.001357209 | 5 | 0 | BeFree |
| Asthma | 0.001085767 | 4 | 0 | BeFree |
| Malignant tumor of colon | 0.001085767 | 4 | 0 | BeFree |
| Influenza | 0.001085767 | 4 | 0 | BeFree |
| Leukemia, Myelocytic, Acute | 0.001085767 | 4 | 0 | BeFree |
| melanoma | 0.001085767 | 4 | 0 | BeFree |
| Astrocytoma | 0.000814326 | 3 | 0 | BeFree |
| Malignant neoplasm of urinary bladder | 0.000814326 | 3 | 0 | BeFree |
| Non-Small Cell Lung Carcinoma | 0.000814326 | 3 | 0 | BeFree |
| Exanthema | 0.000814326 | 3 | 0 | BeFree |
| Fibroid Tumor | 0.000814326 | 3 | 0 | BeFree |
| Obesity | 0.000814326 | 3 | 0 | BeFree |
| Uterine Fibroids | 0.000814326 | 3 | 0 | BeFree |
| Pancreatic carcinoma | 0.000814326 | 3 | 0 | BeFree |
| Malignant neoplasm of lung | 0.000814326 | 3 | 0 | BeFree |
| Secondary malignant neoplasm of liver | 0.000814326 | 3 | 0 | BeFree |
| Carcinoma of lung | 0.000814326 | 3 | 0 | BeFree |
| Colon Carcinoma | 0.000814326 | 3 | 0 | BeFree |
| Carcinoma of bladder | 0.000814326 | 3 | 0 | BeFree |
| Spots on skin | 0.000814326 | 3 | 0 | BeFree |
| Allergic rhinitis (disorder) | 0.000814326 | 3 | 0 | BeFree |
| Congenital Abnormality | 0.000542884 | 2 | 0 | BeFree |
| Bronchogenic Carcinoma | 0.000542884 | 2 | 0 | BeFree |
| Squamous cell carcinoma | 0.000542884 | 2 | 0 | BeFree |
| Coronary heart disease | 0.000542884 | 2 | 0 | BeFree |
| Dengue Fever | 0.000542884 | 2 | 0 | BeFree |
| Diabetic Nephropathy | 0.000542884 | 2 | 0 | BeFree |
| Endometriosis | 0.000542884 | 2 | 0 | BeFree |
| Gastrinoma | 0.000542884 | 2 | 0 | BeFree |
| Hepatitis, Chronic | 0.000542884 | 2 | 0 | BeFree |
| Herpes Simplex Infections | 0.000542884 | 2 | 0 | BeFree |
| Liver Cirrhosis | 0.000542884 | 2 | 0 | BeFree |
| Neoplasm Metastasis | 0.000542884 | 2 | 0 | BeFree |
| Retinoblastoma | 0.000542884 | 2 | 0 | BeFree |
| Virus Diseases | 0.000542884 | 2 | 0 | BeFree |
| Pancreatitis, Chronic | 0.000542884 | 2 | 0 | BeFree |
| Scab | 0.000542884 | 2 | 0 | BeFree |
| Malignant neoplasm of pancreas | 0.000542884 | 2 | 0 | BeFree |
| Secondary malignant neoplasm of lymph node | 0.000542884 | 2 | 0 | BeFree |
| Mammary Neoplasms | 0.000542884 | 2 | 0 | BeFree |
| Cirrhosis | 0.000542884 | 2 | 0 | BeFree |
| Adenocarcinoma | 0.000271442 | 1 | 0 | BeFree |
| Adenoma | 0.000271442 | 1 | 0 | BeFree |
| Ataxia Telangiectasia | 0.000271442 | 1 | 0 | BeFree |
| Autoimmune Diseases | 0.000271442 | 1 | 0 | BeFree |
| Bipolar Disorder | 0.000271442 | 1 | 0 | BeFree |
| Blepharoptosis | 0.000271442 | 1 | 0 | BeFree |
| Noninfiltrating Intraductal Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Cardiomyopathy, Dilated | 0.000271442 | 1 | 0 | BeFree |
| Choroideremia | 0.000271442 | 1 | 0 | BeFree |
| Colitis | 0.000271442 | 1 | 0 | BeFree |
| Colorectal Neoplasms | 0.000271442 | 1 | 0 | BeFree |
| Encephalitis Lethargica | 0.000271442 | 1 | 0 | BeFree |
| IGA Glomerulonephritis | 0.000271442 | 1 | 0 | BeFree |
| Heart Diseases | 0.000271442 | 1 | 0 | BeFree |
| Hemophilia A | 0.000271442 | 1 | 0 | BeFree |
| Hepatitis | 0.000271442 | 1 | 0 | BeFree |
| Hepatitis A | 0.000271442 | 1 | 0 | BeFree |
| Hepatitis, Alcoholic | 0.000271442 | 1 | 0 | BeFree |
| Hyperthyroidism | 0.000271442 | 1 | 0 | BeFree |
| Hypothyroidism | 0.000271442 | 1 | 0 | BeFree |
| Inflammatory Bowel Diseases | 0.000271442 | 1 | 0 | BeFree |
| Keratoconus | 0.000271442 | 1 | 0 | BeFree |
| Acute lymphocytic leukemia | 0.000271442 | 1 | 0 | BeFree |
| Leukemia, Lymphocytic, Acute, L1 | 0.000271442 | 1 | 0 | BeFree |
| Myeloid Leukemia, Chronic | 0.000271442 | 1 | 0 | BeFree |
| Leukodystrophy, Metachromatic | 0.000271442 | 1 | 0 | BeFree |
| Lymphoma | 0.000271442 | 1 | 0 | BeFree |
| Meningioma | 0.000271442 | 1 | 0 | BeFree |
| Spinal Muscular Atrophy | 0.000271442 | 1 | 0 | BeFree |
| Pheochromocytoma | 0.000271442 | 1 | 0 | BeFree |
| Pituitary Diseases | 0.000271442 | 1 | 0 | BeFree |
| Polycystic Ovary Syndrome | 0.000271442 | 1 | 0 | BeFree |
| Adenomatous Polyposis Coli | 0.000271442 | 1 | 0 | BeFree |
| Pregnancy in Diabetics | 0.000271442 | 1 | 0 | BeFree |
| Ptosis | 0.000271442 | 1 | 0 | BeFree |
| Rett Syndrome | 0.000271442 | 1 | 0 | BeFree |
| Schizophrenia | 0.000271442 | 1 | 0 | BeFree |
| Seminoma | 0.000271442 | 1 | 0 | BeFree |
| B-Cell Lymphomas | 0.000271442 | 1 | 0 | BeFree |
| Severe Combined Immunodeficiency | 0.000271442 | 1 | 0 | BeFree |
| Small cell carcinoma of lung | 0.000271442 | 1 | 0 | BeFree |
| Thyroid Gland Follicular Adenoma | 0.000271442 | 1 | 0 | BeFree |
| Atrophic condition of skin | 0.000271442 | 1 | 0 | BeFree |
| Disease of mucous membrane | 0.000271442 | 1 | 0 | BeFree |
| Secondary malignant neoplasm of lung | 0.000271442 | 1 | 0 | BeFree |
| Old myocardial infarction | 0.000271442 | 1 | 0 | BeFree |
| HELLP Syndrome | 0.000271442 | 1 | 0 | BeFree |
| Follicular adenoma | 0.000271442 | 1 | 0 | BeFree |
| Hepatoblastoma | 0.000271442 | 1 | 0 | BeFree |
| Gallbladder Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Mucosa-Associated Lymphoid Tissue Lymphoma | 0.000271442 | 1 | 0 | BeFree |
| Bronchiolitis Obliterans Organizing Pneumonia | 0.000271442 | 1 | 0 | BeFree |
| Carcinoma, Small Cell | 0.000271442 | 1 | 0 | BeFree |
| Parathyroid Adenoma | 0.000271442 | 1 | 0 | BeFree |
| Pachygyria | 0.000271442 | 1 | 0 | BeFree |
| Hyperphosphaturia | 0.000271442 | 1 | 0 | BeFree |
| Parathyroid hyperplasia | 0.000271442 | 1 | 0 | BeFree |
| Qualitative abnormality of granulocyte | 0.000271442 | 1 | 0 | BeFree |
| Gastric Adenocarcinoma | 0.000271442 | 1 | 0 | BeFree |
| Adenocarcinoma Of Esophagus | 0.000271442 | 1 | 0 | BeFree |
| Laryngeal Squamous Cell Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Adenocarcinoma of pancreas | 0.000271442 | 1 | 0 | BeFree |
| Phosphate Diabetes | 0.000271442 | 1 | 0 | BeFree |
| High altitude pulmonary edema | 0.000271442 | 1 | 0 | BeFree |
| Dystonia Disorders | 0.000271442 | 1 | 0 | BeFree |
| Metabolic Syndrome X | 0.000271442 | 1 | 0 | BeFree |
| Carcinogenesis | 0.000271442 | 1 | 0 | BeFree |
| Hemophilia, NOS | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm tonsil | 0.000271442 | 1 | 0 | BeFree |
| Hypoxic-Ischemic Encephalopathy | 0.000271442 | 1 | 0 | BeFree |
| Helicobacter pylori infection | 0.000271442 | 1 | 0 | BeFree |
| Invasive breast carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Endometrial adenocarcinoma | 0.000271442 | 1 | 0 | BeFree |
| Ductal Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Precursor B-cell lymphoblastic leukemia | 0.000271442 | 1 | 0 | BeFree |
| Infiltrating Cervical Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Glioblastoma Multiforme | 0.000271442 | 1 | 0 | BeFree |
| Benign Prostatic Hyperplasia | 0.000271442 | 1 | 0 | BeFree |
| Cerebrofrontofacial Syndrome | 0.000271442 | 1 | 0 | BeFree |
| Fryns-Aftimos Syndrome | 0.000271442 | 1 | 0 | BeFree |
| Precursor Cell Lymphoblastic Leukemia Lymphoma | 0.000271442 | 1 | 0 | BeFree |
| Regurgitation | 0.000271442 | 1 | 0 | BeFree |
| Motor disturbances | 0.000271442 | 1 | 0 | BeFree |
| Severe hypoxic ischemic encephalopathy | 0.000271442 | 1 | 0 | BeFree |
| Primary immunoglobulin A nephropathy (disorder) | 0.000271442 | 1 | 0 | BeFree |
| Nonalcoholic Steatohepatitis | 0.000271442 | 1 | 0 | BeFree |
| Familial Hypophosphatemic Rickets | 0.000271442 | 1 | 0 | BeFree |
| Vitamin D-Resistant Rickets, X-Linked | 0.000271442 | 1 | 0 | BeFree |
| Intellectual Disability | 0.000271442 | 1 | 0 | BeFree |
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