ACR(acrosin) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

22q13.33
基因染色体位置图

基因简述

基因简述

Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  顶体存在于成熟精子的顶体的主要蛋白酶。它是一种典型的丝氨酸蛋白酶具有类似胰蛋白酶的特异性。它存储在它的前体形式的顶体，proacrosin。在透明带的溶解的活性酶的功能，从而通过卵子的最内糖蛋白层促进精子的渗透。对于proacrosin mRNA的仅在精子发生的postmeiotic阶段合成。在人类proacrosin在单倍体精子第一次出现。 [由RefSeq的，2008年7月提供]

OMIM数据库中对ACR基因的介绍     Wikipedia数据库中对ACR基因的介绍

基因序列

基因序列

ACR基因的碱基序列：[NCBI]

基因突变

基因突变

ACR基因的碱基突变：           显示全部snp
rs1064733       rs1064734       rs1064735       rs1064736       rs1858748       rs2283675       rs2283676       rs2285395       rs3788733       rs3810648       rs4040042       rs4040045       rs4040046       rs5770999       rs5771000       rs5771002       rs6009960       rs6009961       rs6010067       rs6010068       rs6010069       rs6010070       rs6010071       rs6010072       rs6010073       rs6010074       rs7289636       rs7289817       rs9616824       rs9616825       rs9616953       rs9616954       rs9616955       rs11705587       rs12165648       rs13056271       rs13056621      
rs13058566       rs13058575       rs28516879       rs34756634       rs56180343       rs56238942       rs56704331       rs56807126       rs57763389       rs58109483       rs59998603       rs60087616       rs71198273       rs71232632       rs71232633       rs71232634       rs71318831       rs71318832       rs73174435       rs73174436       rs73174437       rs73433406       rs75020145       rs75224308       rs75385660       rs75519438       rs76593947       rs76866150       rs77216309       rs77313877       rs78827609       rs79314756       rs111410492       rs112131405       rs113204118       rs113782494       rs113857899       rs114634361       rs115360146       rs116026001       rs116139503       rs138662706       rs138777072       rs138972118       rs139320040       rs139648296       rs139675699       rs140035017       rs140108120       rs140237069       rs140364806       rs140584689       rs140628153       rs141343944       rs141844965       rs141891250       rs142455527       rs142494818       rs142530125       rs142763472       rs143366653       rs143550602       rs143887109       rs144573414       rs145267492       rs145373249       rs145715949       rs145756479       rs145800154       rs146016475       rs146034851       rs146416000       rs146594596       rs146686428       rs146910789       rs147392791       rs148453082       rs149136358       rs149456732       rs149554062       rs149767101       rs150059289       rs150273293       rs150628453       rs151010076       rs151269264       rs181184416       rs181504904       rs182021876       rs182137879       rs182163802       rs182889325       rs183029053       rs183538550       rs184104408       rs184517959       rs184754227       rs185024095       rs185375060       rs185550366       rs185832541       rs186157598       rs186986450       rs187441595       rs188103638       rs188316052       rs188459010       rs188568125       rs188713481       rs189214490       rs189228274       rs189966119       rs190253671       rs190644757       rs190654794       rs190741616       rs191131410       rs191165317       rs191736410       rs192232940       rs192585036       rs192588390       rs192800892       rs193183499       rs199699640       rs200076103       rs200079264       rs200217266       rs200602661       rs200667515       rs200755264       rs200978349       rs201146734       rs201174415       rs201494682       rs201614140       rs201620831       rs201653264       rs202122603       rs367645902       rs367707815       rs367772352       rs368095098       rs368346881       rs368378183       rs368687098       rs368710046       rs368795913       rs368884202       rs369405326       rs369793555       rs370250594       rs370903765       rs371144846       rs371232787       rs371591031       rs371960370       rs372103471       rs372139399       rs372838594       rs373285057       rs373637798       rs373978674       rs374054353       rs374344475       rs374353191       rs374489453       rs374561247       rs374583693       rs374895009       rs375173325       rs375611642       rs375672952       rs375955669       rs376097535       rs376116447       rs376149615       rs376377088       rs376638753       rs376947740       rs377686251       rs377757183       rs377766496       rs527485150       rs527547847       rs527557266       rs527816556       rs527895727       rs527929275       rs528073121       rs528705561       rs528817812       rs528859748       rs529480798       rs529516526       rs529634516       rs529658418       rs529759680       rs530422080       rs531270968       rs531525864       rs531590003       rs531602050       rs531697145       rs532034396       rs532266159       rs532366709       rs532492952       rs532493903       rs532532091       rs533106887       rs533574975       rs533580620       rs533639735       rs533675664       rs533978668       rs534865112       rs534928940       rs535147335       rs535209855       rs535800849       rs535864962       rs536466998       rs536547787       rs537267372       rs537269679       rs537374868       rs537381074       rs537612569       rs537842685       rs538030731       rs538588579       rs538661253       rs539010650       rs539644463       rs539800543       rs539806347       rs539860870       rs539971684       rs541083098       rs541508931       rs541570550       rs541875185       rs542019493       rs542768239       rs543333675       rs543558926       rs543573740       rs543728233       rs543789048       rs545565693       rs545669049       rs545764593       rs547117997       rs547219491       rs547314034       rs547752864       rs547756808       rs547919376       rs548483829       rs549073643       rs549188116       rs549620951       rs549738908       rs549849678       rs549879096       rs550216074       rs550289363       rs550472969       rs551425148       rs551559294       rs551891478       rs552492918       rs552673604       rs552705598       rs553195278       rs553367757       rs553429158       rs553493855       rs553853012       rs554811229       rs554850342       rs554924256       rs555242457       rs555446916       rs556159678       rs556161514       rs556669773       rs556772321       rs557426398       rs557489719       rs557498178       rs557559974       rs557606417       rs558096087       rs558567036       rs558575609       rs558691256       rs558788452       rs558801162       rs558973192       rs558985900       rs559202131       rs559530901       rs560352934       rs560418171       rs560657380       rs560771246       rs561007690       rs561113791       rs561125819       rs561127825       rs561360072       rs561458456       rs562391905       rs562972445       rs563065475       rs563101047       rs563162908       rs563164882       rs563656371       rs564577183       rs564641516       rs564842114       rs565026706       rs565135205       rs565161170       rs565170285       rs565587762       rs566306098       rs566336779       rs566606362       rs566641496       rs566704451       rs566904135       rs567274094       rs567369972       rs567383899       rs567496505       rs567613638       rs567680767       rs568537912       rs568766204       rs568829535       rs569329561       rs569338043       rs569387099       rs570026811       rs570941870       rs571003230       rs571073375       rs571079622       rs571196737       rs571275122       rs571337427       rs571994901       rs572808240       rs573608114       rs573618981       rs573656041       rs573717734       rs574332281       rs574817127       rs574848361       rs574883550       rs575525569       rs576205495       rs576305494       rs576896841       rs576958122       rs577036924       rs577242211       rs745321671       rs745401505       rs745566551       rs745668431       rs745773446       rs745849346       rs746236075       rs746332641       rs746465875       rs746535553       rs746623562       rs746907799       rs747512314       rs748010379       rs748013634       rs748269754       rs748292755       rs748359489       rs748714084       rs748800676       rs748831621       rs748842598       rs748915614       rs749100276       rs749387749       rs749779182       rs749856990       rs749966445       rs750066687       rs750250410       rs750341976       rs750430072       rs750510857       rs750598701       rs750829387       rs750946811       rs750963565       rs751041785       rs751206114       rs751237730       rs751325618       rs751572898       rs751888231       rs751977982       rs752065858       rs752153585       rs752210268       rs752296315       rs752344889       rs752661510       rs752749366       rs753029481       rs753102410       rs753117359       rs753355839       rs753399462       rs753445401       rs753600221       rs753687071       rs753779110       rs753852152       rs753863297       rs753952686       rs753955522       rs754127030       rs754365030       rs754487434       rs754575463       rs754872586       rs754950350       rs755241889       rs755259237       rs755580816       rs755668971       rs755756962       rs755928242       rs755978747       rs756016268       rs756156988       rs756276159       rs756365879       rs756717420       rs756980083       rs757077646       rs757077839       rs757283834       rs757370779       rs757452300       rs757599261       rs757885469       rs758174442       rs758320621       rs758342310       rs758522868       rs758733691       rs758877939       rs759056819       rs759261860       rs759273323       rs759347367       rs759591814       rs759643616       rs759769240       rs759858900       rs759954390       rs759992075       rs760115224       rs760312303       rs760400398       rs760402111       rs760673254       rs760775514       rs760865181       rs760951346       rs761053255       rs761459979       rs761928464       rs762191368       rs762191835       rs762197888       rs762486601       rs762663990       rs762710319       rs762982880       rs762995513       rs763545017       rs763566499       rs763738146       rs763968728       rs764062054       rs764169031       rs764251990       rs764339107       rs764583729       rs764625183       rs764777015       rs764818978       rs765266010       rs765298967       rs765300537       rs765386919       rs765479356       rs765565348       rs765659275       rs765797656       rs765965924       rs766145603       rs766169568       rs766233441       rs766256979       rs766337786       rs766454837       rs766540744       rs766680744       rs766935029       rs767026641       rs767101826       rs767185949       rs767321569       rs767471439       rs767699984       rs768038088       rs768051648       rs768141356       rs768256291       rs768316186       rs768356443       rs768599127       rs768837972       rs768927642       rs768927847       rs769015823       rs769050148       rs769069119       rs769408924       rs769428134       rs769494886       rs769574426       rs769598996       rs769712642       rs769803264       rs769870090       rs769944788       rs770176712       rs770545157       rs770629027       rs770906540       rs770971394       rs771278254       rs771324284       rs771560591       rs771650407       rs771831167       rs771921211       rs772050251       rs772193783       rs772341597       rs772863293       rs772960200       rs773155267       rs773349529       rs773438105       rs773463145       rs773554712       rs773984711       rs774080258       rs774203834       rs774484543       rs774572935       rs774583534       rs774592702       rs774682505       rs774951543       rs774985222       rs775250607       rs775336676       rs775696022       rs776024191       rs776104441       rs776109873       rs776310766       rs776389360       rs776401590       rs776876305       rs776906749       rs776994517       rs777321406       rs777620745       rs777704545       rs777783945       rs778269132       rs778272693       rs778557423       rs778727557       rs778905832       rs778958003       rs779604343       rs779879875       rs779896154       rs779986070       rs780466256       rs780473655       rs780653208       rs780676985       rs780839734       rs780842035       rs781206179       rs781212788       rs781318255       rs781501868       rs781571885       rs781661587       rs781703331      

基因表达

基因表达

ACR基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
ATAATGTGCATGACTGGAGAC
58
GCCTTTACTGGTTTATTGTTCC
58
TAGAAGAGAAAGGCTTCCTGG
59
GACAGAGCTCTAGAGCGAC
59
AATAATGTGCATGACTGGAGAC
59
CCTTTACTGGTTTATTGTTCCC
57
GAATTCACGATGGGTGCTC
59
AACCAGTCTCCAGTCATGC
60
CTGTAGGCAAGATCGACAC
58
CTGTCTTTGCACATGAGAGG
59
TGTAGGCAAGATCGACACC
60
CTGGGAGGACAATTTCCAC
58
TATAGAAGAGAAAGGCTTCCTGG
60
CAGAGCTCTAGAGCGACAG
59
TGAATTCACGATGGGTGCT
60
AACCAGTCTCCAGTCATGC
60
ATCCTGTAGGCAAGATCGAC
59
GAGGACAATTTCCACAGTGAC
59
CTGAATTCACGATGGGTGC
59
AACCAGTCTCCAGTCATGC
60

转录因子

转录因子

      尚未收录相关数据

基因本体信息

ACR基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

ACR基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0001669
E9PLV5(UniProtKB)
IEA
GO:0004252
E9PLV5(UniProtKB)
IEA
GO:0006508
E9PLV5(UniProtKB)
IEA
GO:0002020
P10323(UniProtKB)
TAS
GO:0002077
P10323(UniProtKB)
NAS
GO:0003677
P10323(UniProtKB)
NAS
GO:0004040
P10323(UniProtKB)
ISS
GO:0004252
P10323(UniProtKB)
IDA
GO:0005507
P10323(UniProtKB)
NAS
GO:0005515
P10323(UniProtKB)
IPI
GO:0005515
P10323(UniProtKB)
IPI
GO:0005515
P10323(UniProtKB)
IPI
GO:0005515
P10323(UniProtKB)
IPI
GO:0005537
P10323(UniProtKB)
IDA
GO:0005576
P10323(UniProtKB)
TAS
GO:0005576
P10323(UniProtKB)
TAS
GO:0005634
P10323(UniProtKB)
IDA
GO:0005798
P10323(UniProtKB)
IEA
GO:0007190
P10323(UniProtKB)
IDA
GO:0007338
P10323(UniProtKB)
ISS
GO:0007339
P10323(UniProtKB)
IEA
GO:0007340
P10323(UniProtKB)
IMP
GO:0007340
P10323(UniProtKB)
TAS
GO:0008144
P10323(UniProtKB)
ISS
GO:0008270
P10323(UniProtKB)
NAS
GO:0042806
P10323(UniProtKB)
ISS
GO:0043159
P10323(UniProtKB)
TAS
GO:0043234
P10323(UniProtKB)
IDA
GO:0048545
P10323(UniProtKB)
IEA
GO:0007341
P10323(UniProtKB)
IDA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控ACR基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Rheumatoid Arthritis 0.005700279 21 10 BeFree
Lupus Erythematosus, Systemic 0.003257302 12 0 BeFree
Lupus Vulgaris 0.000542884 2 0 BeFree
Lupus Erythematosus, Discoid 0.000542884 2 0 BeFree
Systemic Scleroderma 0.000542884 2 0 BeFree
Lupus Erythematosus 0.000542884 2 0 BeFree
Anemia 0.000271442 1 0 BeFree
Anemia, Hemolytic 0.000271442 1 0 BeFree
Fibromyalgia 0.000271442 1 0 BeFree
Hematological Disease 0.000271442 1 0 BeFree
leukemia 0.000271442 1 0 BeFree
Leukemia, Myelocytic, Acute 0.000271442 1 0 BeFree
Myeloid Leukemia, Chronic 0.000271442 1 0 BeFree
Lymphoma 0.000271442 1 0 BeFree
Rheumatism 0.000271442 1 0 BeFree
Carcinogenesis 0.000271442 1 0 BeFree
Microalbuminuria 0.000271442 1 0 BeFree

基因相关文献

基因相关文献

基因相关服务

基因相关服务

基因评论

基因评论

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