更多...
收起
The protein encoded by this gene catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. The encoded protein, which is a type II membrane protein found in the Golgi, is also required for the synthesis of the bacterial verotoxins receptor. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  由该基因编码的蛋白质催化的半乳糖转移到乳糖苷神经酰胺以形成globotriaosylceramide,这已被确定为在P血型系统中的P(k)的抗原。所编码的蛋白质,它是在高尔基体中发现II型膜蛋白,也需要在细菌vero毒素受体的合成。 [由RefSeq的,2008年7月提供]
A4GALT基因(以及对应的蛋白质)的细胞分布位置:
A4GALT基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Burkitt Lymphoma | 0.12 | 1 | 0 | CTD_human |
Cortical Congenital Hyperostosis | 0.12 | 0 | 0 | CLINVAR |
Blood group p phenotype (finding) | 0.12 | 0 | 7 | CLINVAR |
Hemolytic-Uremic Syndrome | 0.00272435 | 1 | 0 | LHGDN |
leukemia | 0.00272435 | 1 | 0 | LHGDN |
Acute Megakaryocytic Leukemias | 0.000271442 | 1 | 0 | BeFree |
Teratocarcinoma | 0.000271442 | 1 | 0 | BeFree |
Uremia syndrome | 0.000271442 | 1 | 0 | BeFree |
Hematopoietic Neoplasms | 0.000271442 | 1 | 0 | BeFree |
忘记密码? 点击找回密码.
扫一扫右方二维码,关注微信订阅号,实时查看信息,关注医学生物学动态。