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METTL3-mediated TIGAR m6A modification and its role in microglia activation r...

Kang(J),Du(X),Zhang(X),Li(Y),Wang(C),Sun(S... Neuroreport 2026-03-18

...TIGAR). Human microglia HMC3 cells were transfected with overexpression or knockdown lentivirus of METTL3, TIGAR, or TIG...

Understanding the Pathophysiology of Chronic Pancreatitis: A Comprehensive Re...

Sekhar(AC),Kandhi(S),Ramaswamy(P),Thyagara... J Clin Med 2026-05-15

...TIGAR-O classification system: toxin-related, idiopathic, genetic mutations, autoimmune disorders, episodes of recurrent...

YTHDF1-mediated translational activation of SETD2 suppresses aerobic glycolys...

Xu(S),Huang(B),Lin(H),Liu(Z),Pan(Z),Chen(J... Cell Signal 2026-08-26

...TIGAR metabolic checkpoint to block aerobic glycolysis. Disruption of the YTHDF1/SETD2/p53 axis induces enhanced glycoly...

Glycolytic reprogramming in precancerous lesions of gastric cancer progressio...

Niu(S),Sun(H),Wang(Z),Jin(Q),Sun(Z),Yu(D),... Front Oncol None

...TIGAR pathway, and p57. These metabolic alterations may promote PLGC progression through an imbalance between proliferat...

Proteomic Analysis of TCGA Data Reveals Limited Prognostic Value of p53 but S...

Toennießen-Klein(SM),Rangno(D),Sunil(A),Bo... Int J Mol Sci 2026-07-27

...TIGAR) were assessed using reverse-phase protein array (RPPA) data. Survival analyses were performed using Kaplan-Meier ...

Dual-functional copper nanoplatform potentiates cuproptosis through p53 react...

Ma(L),Zheng(H),Xie(W),Sun(W),Yuan(Q),Song(... J Colloid Interface Sci 2026-03-15

...TIGAR) and glutaminase 2 (GLS2), suppresses glycolysis, and enhances tricarboxylic acid (TCA) cycle flux, thereby sensit...

Prospective Breast Cancer Biomarkers Identified Using miR-526b-Driven Metabol...

Nault(B),Majumder(M) Cancer Inform None

...TIGAR that may help to identify additional biomarkers for breast cancer detection. We analyzed mRNA expression of these ...

Study on the role of TIGAR in regulating mitochondrial function and inhibitin...

Lu(M),Zhai(MY),Wang(PY),Li(HN),Li(X),Lin(P... Free Radic Biol Med 2026-03-01

...TIGAR) inhibited nigericin-induced pyroptosis in TNBC cells, whereas knockdown of TIGAR significantly augmented the leve...

Design, synthesis, and evaluation of novel andrographolide derivatives as ant...

Li(YR),Chiang(PY),Hou(SY),Lin(CH),Lo(LC),F... Bioorg Chem 2026-08-15

...TIGAR, and MYC. Fluorescent signals of compound 4 were detectable within 5 min and remained stable for 48 h after incuba...

TIGAR overexpression alleviates intracerebral hemorrhage injury in mice by su...

Li(YY),Yuan(JR),Tang(J),Chen(L),Wu(JC),Qin... Acta Pharmacol Sin 2026-09-00

...TIGAR protein expression in the striatum of ICH mice with increased distribution of TIGAR protein among neurons, microgl...

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