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Reversal of the malignant phenotype of gastric cancer cells by inhibition of Rh…

Liu(N),Bi(F),Pan(Y),Sun(L),Xue(Y),Shi(Y),Yao… Clin Cancer Res 2004-09-15

...RhoA mutant suppression of endogenous RhoA activity. RhoA was found frequently overexpressed in gastric cancer tissues a...

RhoA Proteolysis Regulates the Actin Cytoskeleton in Response to Oxidative Stre…

Girouard(MP),Pool(M),Alchini(R),Rambaldi(I),… PLoS One 2016-00-00

...RhoA. Here, we describe a novel mechanism of RhoA proteolysis that generates a stable amino-terminal RhoA fragment (RhoA...

Unique in vivo associations with SmgGDS and RhoGDI and different guanine nucleo…

Strassheim(D),Porter(RA),Phelps(SH),Williams… J Biol Chem 2000-03-10

...RhoA, and to a lesser extent with RhoA(Val-14), but does not detectably co-precipitate with RhoA(Asn-19). Wild-type RhoA...

Mechanisms of inactivation of the tumour suppressor gene RHOA in colorectal can…

Dopeso(H),Rodrigues(P),Bilic(J),Bazzocco(S),… Br J Cancer 2018-00-00

...RHOA, as well as the presence of RHOA mutations/deletions and promoter methylation affecting RHOA. Changes in RHOA expre...

Negative regulation of RhoA translation and signaling by hnRNP-Q1 affects cellu…

Xing(L),Yao(X),Williams(KR),Bassell(GJ) Mol Biol Cell 2012-04-00

...RhoA expression and the subsequent effects on RhoA signaling. We hypothesized that posttranscriptional control of RhoA e...

RhoA promotes epidermal stem cell proliferation via PKN1-cyclin D1 signaling.

Wang(F),Zhan(R),Chen(L),Dai(X),Wang(W),Guo(R… PLoS One 2017-00-00

...RhoA(+/+)(G14V), RhoA(-/-)(T19N) and pGFP control plasmids were transfected into human ESCs. The effect of RhoA on cell ...

Functions of RhoA in the female reproductive system.

Sundgren(JK),Martin(TE),Viswanathan(S),Atlur… Reprod Dev Med 2025-09-00

...RhoA in cervical cancer. In the placenta, RhoA is implicated in preeclampsia and placenta accreta. In the vagina, RhoA d...

Phosphorylation and Activation of RhoA by ERK in Response to Epidermal Growth F…

Tong(J),Li(L),Ballermann(B),Wang(Z) PLoS One 2016-00-00

...RhoA. EGF stimulation enhanced the activation of the endogenous RhoA. The phosphomimetic mutant, GFP-RhoA S88E/T100E, wh...

Tyr42 phosphorylation of RhoA GTPase promotes tumorigenesis through nuclear fac…

Kim(JG),Choi(KC),Hong(CW),Park(HS),Choi(EK),… Free Radic Biol Med 2017-00-00

...RhoA WT and phospho-mimic RhoA, RhoA Y42E, both promoted tumorigenesis, whereas the dephospho-mimic RhoA, RhoA Y42F supp...

Function of a complex of p-Y42 RhoA GTPase and pyruvate kinase M2 in EGF signal…

Lee(YB),Park(Y),Hamza(A),Min(JK),Dogsom(O),K… J Neurochem 2025-01-00

...RhoA and p-Y42 RhoA. Importantly, RhoA, p-Y42 RhoA, and PKM2, but not RhoA-GTP, were localized in the nucleus upon EGF s...

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