Li(M),Chen(Y),Liu(A),Wu(Q),Huang(C),Song(D... Cancer Res 2026-05-04

...PPM1A, inhibiting SMAD3 dephosphorylation and thereby sustaining TGFβ-SMAD3 signaling. Persistent SMAD3 activation enhan...

Wang(H),Li(Q),Wang(W),Jin(Z),Tong(X),Zhang... J Med Chem 2026-07-23

...PPM1A phosphatase agonists. SAR analysis confirms the distal xylose removal drastically improves PPM1A agonistic potency...

Li(Y),Zhou(Y),Zhao(P),Shi(M),Wang(Z),Zhang... Am J Respir Cell Mol Biol 2026-08-10

...PPM1A at cysteine 71 enhanced the interaction between PPM1A and Smad2/3, promoted Smad2/3 dephosphorylation, and suppres...

Manjunatha(AT),Shalini(R),Binsila(BK),Kris... Anim Reprod Sci 2026-08-14

...PPM1A, DUSP1, etc.) emerged as the most significant and may suggest that these minerals influence genome packaging and s...

Lee(YH),Nam(Y),Park(K),Ji(H),Kim(JW),Cho(S... Front Pharmacol None

...PPM1A-SMAD interaction and reduced SMAD2/3 phosphorylation, whereas PPM1A knockdown diminished their anti-fibrotic effec...

Yang(C),Harafuji(N),Watts(JA),Tao(B),Moran... Kidney Int 2026-05-00

...PPM1A as a cystin-interacting partner, and pharmacologic inhibition reduced cystin S17 dephosphorylation. Cystin-1 intra...

Song(N),Ling(Y),Zhou(F),Fang(J),Zhao(Y),Zh... J Transl Med 2026-01-07

...PPM1A) enzyme activity was abnormally reduced in both DPN patients and model mice. Treatment with Miltefosine (MF), a PP...

Man(J),Wang(K),Zhang(Y),Wang(H),Xu(C),Yan(... FASEB J 2026-07-31

...PPM1A, FBP1, CDO1, p53, Smad4, and XAF1, whereas through K63-linked ubiquitination it enhances signaling activity of med...

Kircheva(N),Petkova(V),Angelova(S),Dudev(T... Biomolecules 2026-06-11

Protein phosphatase PPM1A plays a critical role in cellular signaling by dephosphorylating key regulatory proteins. Acco...

Luo(Y),Hong(P),Chen(T),Li(Y),Han(Y),Chang(... BMC Genomics 2026-06-18

...PPM1A, Table 2, TGFBR1), forming a total of 24 interactions. This study identified miR-9619-y as a critical negative reg...