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First reported case of developmental dysplasia of the hips in a child with 3M...

Fakeeha(JH),Alotaibi(MA),Alshugair(IF),Alt... J Surg Case Rep 2026-03-00

...CUL7), obscurin-like 1 (OBSL1), and coiled-coil domain containing protein 8 (CCDC8). It is associated with multiple dysm...

Graph-Based Multi-Omics Integration Reveals Prognostic Histone Modification R...

Cui(X),Xue(S),Jiang(P),Shi(L),Tan(T),Xu(Y)... Genes (Basel) 2026-07-23

...CUL7, GPC1, NFYA, SLC25A5) exhibited robust prognostic performance and strong correlations with anti-tumor immunity. Bot...

Interstitial cystitis-related gene CCDC8 accelerates tumorigenesis by partici...

Wang(J),Wang(J),Meng(L),Wang(X),Yan(Z),Pan... Oncogene 2026-03-00

...CUL7, facilitating proteasome-dependent degradation of P53, thereby suppressing its downstream effectors such as P21 and...

A comprehensive analysis of the Cullin family reveals that CUL5 and CUL7 prom...

Al-Dayan(N) Hereditas 2026-04-22

...CUL7. Immunohistochemistry confirmed elevated protein levels, while genomic analysis showed that CUL9, CUL1, and CUL7 ex...

A Novel Homozygous CUL7 Variant in an Iranian Patient Expands the Genetic Spe...

Arefzadeh(M),Rabbani(B),Abdolahpour(S),Ema... Clin Case Rep 2026-03-00

...CUL7 gene identified in an Iranian girl with clinical features consistent with 3MS. Clinical evaluations involved monthl...

CUL7-mediated KEAP1 ubiquitination promotes the progression of colon cancer v...

Shi(L),Shi(F),Zhang(Y),Liu(R),Liu(Q),Zhang... Cell Death Dis 2026-06-08

...CUL7 in colon cancer remain poorly defined. Here, we demonstrate that high CUL7 expression correlates with poor prognosi...

Hepatic TGFβ1 signaling impairs insulin sensitivity via inducing insulin rece...

Ai(W),Pan(Q),Shen(Z),Yang(W),Jiang(W),Song... Metabolism 2026-09-00

...CUL7) expression and promoted IRS1 phosphorylation at serine 685, leading to ubiquitin-dependent IRS1 degradation. Pharm...

Copper(II) complex with a redox-noninnocent Schiff base bearing a tetraphenyl...

Wittmann(C),Palamarciuc(O),Dascalu(M),Caza... Dalton Trans 2025-07-15

...CuL7]+, but not in the [CuL7]2+ one. The doubly oxidised [CuL7] species shows very close doublet and quartet states, whe...

Ankyrin repeats of ANKRA2 recognize a PxLPxL motif on the 3M syndrome protein...

Nie(Jianyun),Xu(Chao),Jin(Jing),Aka(Juliet... Structure 2016-01-01

...CUL7 and OBSL1. While CUL7 is a ubiquitin ligase and OBSL1 associates with the cytoskeleton, little is known about CCDC8...

Inhibition of HIV-1 assembly by coiled-coil domain containing protein 8 in hu...

Wei(Min),Zhao(Xia),Liu(Mi),Huang(Zhi),Xiao... Sci Rep 2016-08-19

...Cul7, induces Gag polyubiquitination and degradation. Thus we identify a new host protein and a new pathway for HIV-1 Ga...

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