...BRCA1 mutations were screened for allelic loss in tumor DNA at the BRCA1 locus.,Two of the 17 patients (11%, 95% confide...
...BRCA1 antibodies. Each of the antibodies specifically detected BRCA1 as localized to specific nuclear domains and did so...
...BRCA1 function. BAP1 binds to the wild-type BRCA1-RING finger, but not to germline mutants of the BRCA1-RING finger foun...
...BRCA1 gene. We found no evidence of methylation at CpGs within the BRCA1 promoter in a variety of normal human tissues. ...
...BRCA1 is not warranted. In contrast, BRCA1 mutations are sufficiently frequent in families with both breast and ovarian ...
...BRCA1 status, these findings on women drawn from the general population suggest that it may be difficult to develop BRCA...
...BRCA1 or BRCA2, by likelihood calculations that take into account information from the entire pedigree. This genetic ris...
...BRCA1), mutations of codon 12 of Ki-ras and immunohistochemical expression of the p53 and c-erbB2 gene products in endom...
...BRCA1. These results suggest that the clinical outcome of ovarian cancer with germ-line mutations of BRCA1 appears to be...
...BRCA1. Through this work, a kinase activity which co-purifies with BRCA1 has been identified. This kinase activity, whic...
山东省济南市章丘区文博路2号
齐鲁师范学院 genelibs生信实验室
山东省济南市高新区舜华路750号
大学科技园北区F座4单元2楼
电话: 0531-88819269