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BRCA1-related breast cancer in Austrian breast and ovarian cancer families: s...

Wagner(T M),Möslinger(R A),Muhr(D),Langbau... Int J Cancer 1998-07-28

...BRCA1 mutations were further analyzed. We observed a low median age of onset (39.5 years). Sixty-eight percent of all BR...

Detection of BRCA1 gene mutations in families with breast cancer patients and...

Garcia-Patińo(E),Gomendio(B),Silva(J M),Ga... Int J Oncol 1998-08-14

...BRCA1 gene mutations, and identify healthy carriers. Blood samples from patients and healthy relatives were obtained. Ha...

Steroid receptors in hereditary breast carcinomas associated with BRCA1 or BR...

Loman(N),Johannsson(O),Bendahl(P O),Borg(A... Cancer 1998-07-31

...BRCA1-related cases than in the hereditary cases not related to BRCA1 or BRCA2, but not significantly lower than in the ...

Assessment of the time-tradeoff values for prophylactic mastectomy of women w...

Unic(I),Stalmeier(P F),Verhoef(L C),van Da... Med Decis Making 1998-09-21

Female carriers of the breast-cancer-susceptibility genes BRCA1 and BRCA2 are at high risk for breast cancer (85%). They...

Multifactorial analysis of differences between sporadic breast cancers and ca...

Lakhani(S R),Jacquemier(J),Sloane(J P),Gus... J Natl Cancer Inst 1998-08-26

We have previously demonstrated that breast cancers associated with inherited BRCA1 and BRCA2 gene mutations differ from...

Loss of heterozygosity of BRCA1, BRCA2 and ATM genes in sporadic invasive duc...

Rio(P G),Pernin(D),Bay(J O),Albuisson(E),K... Int J Oncol 1998-12-09

...BRCA1 gene, 22.8% for BRCA2 gene and 40% for ATM. LOH of BRCA1 correlated with high grade tumors (p=0.0005) and negative...

The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein ...

Yu(X),Wu(L C),Bowcock(A M),Aronheim(A),Bae... J Biol Chem 1998-10-15

...BRCA1. These results indicate that the BRCA1-CtIP interaction may be required for tumor suppression by BRCA1.

Genetic pathways of colorectal carcinogenesis rarely involve the PTEN and LKB...

Wang(Z J),Taylor(F),Churchman(M),Norbury(G... Am J Pathol 1998-08-25

...BRCA1 and BRCA2, however, it appears that PTEN and LKB1 mutations can cause cancers when present in the germline, but oc...

Evaluating the genetic risk of breast cancer.

McCance(K L),Jorde(L B) Nurse Pract 1998-11-10

...BRCA1 and BRCA2 genes for adult-onset breast and ovarian cancer.

Psychological distress in women seeking genetic counseling for breast-ovarian...

Audrain(J),Schwartz(M D),Lerman(C),Hughes(... Ann Behav Med 1998-11-18

...BRCA1 testing; and (b) to identify specific demographic, personality, and appraisal factors that contribute to cancer-sp...

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