...BRCA1 mutations were further analyzed. We observed a low median age of onset (39.5 years). Sixty-eight percent of all BR...
...BRCA1 gene mutations, and identify healthy carriers. Blood samples from patients and healthy relatives were obtained. Ha...
...BRCA1-related cases than in the hereditary cases not related to BRCA1 or BRCA2, but not significantly lower than in the ...
Female carriers of the breast-cancer-susceptibility genes BRCA1 and BRCA2 are at high risk for breast cancer (85%). They...
We have previously demonstrated that breast cancers associated with inherited BRCA1 and BRCA2 gene mutations differ from...
...BRCA1 gene, 22.8% for BRCA2 gene and 40% for ATM. LOH of BRCA1 correlated with high grade tumors (p=0.0005) and negative...
...BRCA1. These results indicate that the BRCA1-CtIP interaction may be required for tumor suppression by BRCA1.
...BRCA1 and BRCA2, however, it appears that PTEN and LKB1 mutations can cause cancers when present in the germline, but oc...
...BRCA1 and BRCA2 genes for adult-onset breast and ovarian cancer.
...BRCA1 testing; and (b) to identify specific demographic, personality, and appraisal factors that contribute to cancer-sp...
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