...PIK3CA (PIK3CAH1047R) and Yap (YapS127A) in the mouse liver using hydrodynamic transfection (PIK3CA/Yap). In addition, s...
...PIK3CA tumor mutations (P = 0.363). Clinical responses were seen in 96.3% of 54 evaluable patients, and breast conservin...
...PIK3CA (25.0%), KRAS (13.9%), ERBB2 (4.3%), PTEN (2.8%), RB1 (2.8%), CDKN2A (2.8%), AKT1 (1.4%), CTNNB1 (1.4%) and NRAS ...
...PIK3CA (5.1%). IHC of TOP2A was high in 76% of cases, TOPO1 in 51% and SPARC in 25%; low IHC of ERCC1 was seen in 65%, R...
...PIK3CA, ERBB2, BRAF, ROS1, and RET genesoccurred in 7%, 4%, 2.5%, 1.5%, 1%, 1%, and 1% of cases, respectively. Thus, 79%...
...PIK3CA mutations (and aberrations in other members of the PI3K pathway), alterations in receptor tyrosine kinases (prima...
...PIK3CA mutation) with total pathological complete response (tpCR) at surgery, event-free survival (EFS), and overall sur...
...PIK3CA mutations, in order to assess potential clinical implications.,Tumor samples (n = 182) from the CAPRI-GOIM trial ...
...PIK3CA mutations were identified in 20%, 0%, 0% and 7% of the tumours, respectively.,Lung adenocarcinomas with H-FLAC fe...
...PIK3CA (12%). The median number of alterations per patient was 3 (range, 0-16). Nineteen patients (4%) had no alteration...
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