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Apolo(Andrea B),Vogelzang(Nicholas J),Theo... Am Soc Clin Oncol Educ Book 2016-02-17

...PIK3CA, and TP53 and methylation pathways alone or in combination. Recent data from a large, randomized phase III trial ...

Dienstmann(Rodrigo),Salazar(Ramon),Taberne... Am Soc Clin Oncol Educ Book 2016-02-18

...PIK3CA mutations or KRAS, ERBB2, or MET amplifications, also may confer resistance to cetuximab or panitumumab. Polymorp...

Deluche(Elise),Onesti(Elisa),Andre(Fabrice... Am Soc Clin Oncol Educ Book 2016-02-15

...PIK3CA mutations (when targeted with alpha-specific PI3K inhibitors) could be considered as promising targets in breast ...

Earl(Julie),Rico(Daniel),Carrillo-de-Santa... BMC Genomics 2016-02-25

...PIK3CA, TP53, and RAS), copy number alterations assessed using high density SNP arrays, uniparental disomy (UPD) events,...

Xiao(Wei),Gao(Zhiyong),Duan(Yixing),Yuan(W... Oncol Rep 2016-03-23

...PIK3CA. Furthermore, we also explored the downstream molecules of miR-19a/PIK3CA signaling. We found that Notch signalin...

Westin(Shannon N),Ju(Zhenlin),Broaddus(Rus... Mol Oncol 2016-08-15

...PIK3CA, PIK3R1, and PTEN mutations, as well as PTEN protein loss by immunohistochemistry, was explored in the context of...

Logan(Greg J),Dabbs(David J),Lucas(Peter C... Breast Cancer Res 2016-01-15

...PIK3CA and c-src, are consistently altered in LCIS. This review focuses on the molecular drivers of lobular carcinoma, a...

Bellmunt(Joaquim),Werner(Lillian),Leow(Jef... PLoS One 2016-02-22

...PIK3CA (9%), FGFR3 (2%), HRAS/KRAS (5%), and CTNNB1 (1%). 66% of patients had some sort of CNV. PIK3CA/AKT/mTOR pathway ...

Uehara(Yuriko),Oda(Katsutoshi),Ikeda(Yuji)... PLoS One 2016-05-02

...PIK3CA mutations and ARID1A expression in CCCs. SNP array analysis classified 13% of CCCs into a cluster with high frequ...

Zhang(Jian-Wei),Qin(Tao),Hong(Shao-Dong),Z... Chin J Cancer 2016-02-19

...PIK3CA) mutation, 1 (1.4%) had Kirsten rat sarcoma viral oncogene homolog (KRAS) mutation, and 1 (1.4%) had simultaneous...