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Undifferentiated pleomorphic sarcoma with co-existence of KRAS/PIK3CA mutations.

Li(Bingcheng),Li(Li),Li(Xiaoying),Wang(Yua... Int J Clin Exp Pathol 2016-06-06

...PIK3CA mutation (1636C > A, Q546K) in the case.

Deregulation of ARID1A, CDH1, cMET and PIK3CA and target-related microRNA exp...

Ibarrola-Villava(Maider),Llorca-Cardeñosa(... Oncotarget 2016-08-22

...PIK3CA, and 14 target-related microRNAs (miRNAs). We compared mRNA and miRNA expression levels among 66 gastric tumor an...

Phosphoinositide 3-kinase-related overgrowth: cellular phenotype and future t...

Parker(Victoria E R),Knox(Rachel G),Zhang(... Lancet 2016-03-01

Somatic activating mutations in PIK3CA, which encodes the p110α catalytic subunit of phosphoinositide-3-kinase (PI3K) ar...

Molecular genetic studies on EGFR, KRAS, BRAF, ALK, PIK3CA, PDGFRA, and DDR2 ...

Huo(Zhen),Wu(Huanwen),Li(Shanqing),Liang(Z... Diagn Pathol 2016-05-27

...PIK3CA, PDGFRA, and DDR2 genes was performed using next-generation sequencing, Sanger sequencing, and quantitative polym...

Sensitivity of KRAS-Mutant Colorectal Cancers to Combination Therapy That Cot...

Ziemke(Elizabeth K),Dosch(Joseph S),Maust(... Clin Cancer Res 2016-10-14

...PIK3CA mutational status. Tolerance, efficacy, and pharmacodynamic evaluation of target modulation were evaluated in res...

Comparison of the Genomic Landscape Between Primary Breast Cancer in African ...

Keenan(Tanya),Moy(Beverly),Mroz(Edmund A),... J Clin Oncol 2016-03-14

...PIK3CA mutations (20.0% v 33.9%; P = .008). Intratumor genetic heterogeneity was greater in African American than white ...

Systematic Analysis of Endometrial Cancer-Associated Hub Proteins Based on Te...

Gao(Huiqiao),Zhang(Zhenyu) Biomed Res Int 2016-06-09

...PIK3CA, PIK3R1, PIK3R2, KRAS, MAPK3, CTNNB1, RELA, JAK2, AKT1, and AKT2.,Our data may help to reveal the molecular mecha...

Evaluation of an Epigenetic Profile for the Detection of Bladder Cancer in Pa...

van Kessel(Kim E M),Van Neste(Leander),Lur... J Urol 2016-06-27

...PIK3CA, FGFR3 (fibroblast growth factor receptor 3), HRAS, KRAS and NRAS.,The combination of TWIST1, ONECUT2 (2 loci) an...

PIK3CA oncogenic mutations represent a major mechanism of resistance to trast...

Black(Jonathan D),Lopez(Salvatore),Cocco(E... Br J Cancer 2016-01-04

...PIK3CA-mutations. Four HER2/neu-amplified USC (2-harbouring wild-type-PIK3CA-genes and 2-harbouring oncogenic-PIK3CA-mut...

Mutational analysis by next generation sequencing of gastric type dysplasia o...

Salomao(Marcela),Luna(Aesis M),Sepulveda(J... Exp Mol Pathol 2016-04-22

...PIK3CA mutation was identified in a GHP with pyloric-type dysplasia, whereas foveolar-type dysplasia carried TP53 mutati...

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