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Huang(Liang),Chen(Sheng),Yang(Wentao),Xu(B... Oncotarget 2016-05-31

...PIK3CA mutated subgroup (69.2% vs.23.5%, p=0.012). No significant difference was observed in the subgroup analysis of TP...

Ma(B B Y),Goh(B C),Lim(W T),Hui(E P),Tan(E... Invest New Drugs 2016-05-12

...PIK3CA mutation and PIK3CA amplification. The dual primary endpoint was objective response rate and 6-month progression-...

Frenel(Jean Sebastien),Carreira(Suzanne),G... Clin Cancer Res 2016-08-01

...PIK3CA and KRAS were the top 3 mutated genes identified, with 18 (41%), 9 (20%), 8 (18%) different mutations, respective...

Yeung(Sai F),Tong(Joanna H M),Law(Peggy P ... J Thorac Oncol 2016-06-13

...PIK3CA, MET, NRAS, MAP2K1, and RIT1 mutations by polymerase chain reaction-direct sequencing. MET amplification and ALK ...

Martelotto(Luciano G),De Filippo(Maria R),... J Pathol 2016-06-06

...PIK3CA and display a heterogeneous constellation of known cancer genes affected by somatic mutations, including MYB, BRA...

Lou(Hong),Villagran(Guillermo),Boland(Jose... Clin Cancer Res 2016-09-15

...PIK3CA gene. This distribution of PIK3CA mutations is distinct from most other cancer types and does not result in the i...

Muller(Etienne),Brault(Baptiste),Holmes(Al... Cancer Med 2016-07-13

...PIK3CA (E545K, E542K) and KRAS (G12D, G13D) and others in FBXW7 (R465C, R505G, R479Q). Mutations have also been found in...

Bai(Jun),Gao(Jinglong),Mao(Zhijun),Wang(Ji... J Hum Genet 2016-09-30

...PIK3CA (9.9%), and additional mutations in BRAF, CTNNB1, ERBB2 and SMAD4 were also detected at lesser frequencies. Thirt...

Ibrahim(Ezzeldin M),Kazkaz(Ghieth A),Al-Ma... Breast Cancer Res Treat 2016-09-22

...PIK3CA mutational status. In this meta-analysis, AHT did not achieve differential benefit according to PIK3CA mutation i...

Schlitter(Anna Melissa),Jang(Kee-Taek),Klö... Mod Pathol 2016-06-15

...PIK3CA (intraductal 6%, invasive 0%), and loss of SMAD4/DPC4 (intraductal 7%, invasive 0%) were rare. No alterations/mut...