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Identification of E545k mutation in plasma from a PIK3CA wild-type metastatic...

Romero(Atocha),Acosta-Eyzaguirre(Daniel),S... Transl Res 2016-03-21

...PIK3CA wild-type primary tumor in which the PIK3CA E545K mutation was identified in both the circulating-free DNA obtain...

[Molecular analysis of sporadic colon cancer].

Hurtado(Claudia),Wielandt(Ana María),Zárat... Rev Med Chil 2016-04-21

...PIK3CA (E542K, E545D, E545K, Q546E, H1047R). BRAF mutations alone or in combination with PIK3CA mutations were observed ...

PIK3CA Somatic Mutation Status in Relation to Patient and Tumor Factors in Ra...

Phipps(Amanda I),Ahnen(Dennis J),Cheng(Ion... Cancer Epidemiol Biomarkers... 2016-03-31

...PIK3CA). We evaluated the relationship of PIK3CA mutation status in colorectal cancer with race/ethnicity, colorectal ca...

Oligonucleotide PIK3CA/Chromosome 3 Dual in Situ Hybridization Automated Assa...

Zhang(Wenjun),Hubbard(Antony),Baca-Parkins... J Mol Diagn 2016-06-06

...PIK3CA amplification and increased phosphatidylinositol 3-kinase (PI3K) pathway activities suggested that PIK3CA gene co...

Spectrum of gene mutations detected by next generation exome sequencing in br...

Preusser(Matthias),Berghoff(Anna S),Koller... Eur J Cancer 2016-04-28

...PIK3CA mutation (2/76, 2.6%), BRAF mutation (1/76, 1.3%) and SMO mutation (1/76, 1.3%). Presence of KRAS mutations was a...

Coordinated Expression of Phosphoinositide Metabolic Genes during Development...

Rapoport(Stanley I),Primiani(Christopher T... PLoS One 2016-04-25

...PIK3CA, and IMPA1 in Group 2, and SACM1L, PI3KR4, INPP5A, SYNJ1, and PLCB1 in Group 3. Ten of the genes change expressio...

A phase II/III randomized study to compare the efficacy and safety of rigoser...

O'Neil(B H),Scott(A J),Ma(W W),Cohen(S J),... Ann Oncol 2016-06-09

...PIK3CA (1 case). No correlation between mutational status and efficacy was detected.,The combination of RIG + GEM failed...

Identification of potential therapeutic targets by molecular profiling of 628...

Jones(Nathaniel L),Xiu(Joanne),Reddy(Sande... Gynecol Oncol 2016-02-01

Therapeutic options are limited for uterine serous carcinoma (USC). TP53, PIK3CA, FBXW7, and ERBB mutations, as well as ...

How should clinicians address intratumour heterogeneity in clear cell renal c...

Soultati(Aspasia),Stares(Mark),Swanton(Cha... Curr Opin Urol 2016-04-26

...PIK3CA and KDM5C).,ITH must be considered in the management of ccRCC with respect to diagnostic procedures, prognostic a...

Next-generation sequencing for molecular diagnosis of lung adenocarcinoma spe...

Qiu(Tian),Guo(Huiqin),Zhao(Huan),Wang(Luhu... Sci Rep 2016-06-20

...PIK3CA mutations. One (1%) sample had a HRAS G12C mutation. Thirty-two (36%) samples (36%) harbored TP53 mutations. Othe...

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