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Lou(Hong),Villagran(Guillermo),Boland(Jose... Clin Cancer Res 2016-09-15

...PIK3CA gene. This distribution of PIK3CA mutations is distinct from most other cancer types and does not result in the i...

Huang(Liang),Chen(Sheng),Yang(Wentao),Xu(B... Oncotarget 2016-05-31

...PIK3CA mutated subgroup (69.2% vs.23.5%, p=0.012). No significant difference was observed in the subgroup analysis of TP...

Ma(B B Y),Goh(B C),Lim(W T),Hui(E P),Tan(E... Invest New Drugs 2016-05-12

...PIK3CA mutation and PIK3CA amplification. The dual primary endpoint was objective response rate and 6-month progression-...

Frenel(Jean Sebastien),Carreira(Suzanne),G... Clin Cancer Res 2016-08-01

...PIK3CA and KRAS were the top 3 mutated genes identified, with 18 (41%), 9 (20%), 8 (18%) different mutations, respective...

Le Rolle(Anne-France),Klempner(Samuel J),G... Oncotarget 2016-08-10

...PIK3CA or other fusion tyrosine kinases. Multiple RET kinase inhibitors were cytotoxic to RET fusion kinase positive can...

Grünewald(Inga),Vollbrecht(Claudia),Meinra... Oncotarget 2016-05-24

...PIK3CA, SMAD4 and members of the ERB family. HRAS mutations accounted for more than 90% of RAS mutations, occurring espe...

Ekinci(Sadiye),Ilgin-Ruhi(Hatice),Dogan(Mu... Genet Test Mol Biomarkers 2016-05-27

...PIK3CA) mutation frequency among nonsmall-cell lung cancer (NSCLC) patients in Turkey. All exons of the PIK3CA gene were...

Millis(Sherri Z),Gatalica(Zoran),Winkler(J... Clin Breast Cancer 2016-08-31

...PIK3CA), v-akt murine thymoma viral oncogene homolog 1 (AKT1), or phosophatase and tensin homolog (PTEN) aberration. TNB...

Xiao(Wei),Gao(Zhiyong),Duan(Yixing),Yuan(W... Oncol Rep 2016-03-23

...PIK3CA. Furthermore, we also explored the downstream molecules of miR-19a/PIK3CA signaling. We found that Notch signalin...

Westin(Shannon N),Ju(Zhenlin),Broaddus(Rus... Mol Oncol 2016-08-15

...PIK3CA, PIK3R1, and PTEN mutations, as well as PTEN protein loss by immunohistochemistry, was explored in the context of...