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Divergence of P53, PTEN, PI3K, Akt and mTOR expression in tonsillar cancer.

Chun(Sang Hoon),Jung(Chan-Kwon),Won(Hye Su... Head Neck 2016-01-14

...PIK3CA, Akt and mTOR.,Twenty-six patients were HPV-positive. Expression of P53 as well as PIK3CA, Akt and mTOR were not ...

Amplicon sequencing of colorectal cancer: variant calling in frozen and forma...

Betge(Johannes),Kerr(Grainne),Miersch(Thil... PLoS One 2016-04-21

...PIK3CA (3) and KRAS (2). A high concordance of FFPE and paired frozen tissue samples was observed in ten matched samples...

Next-generation sequencing for molecular diagnosis of lung adenocarcinoma spe...

Qiu(Tian),Guo(Huiqin),Zhao(Huan),Wang(Luhu... Sci Rep 2016-06-20

...PIK3CA mutations. One (1%) sample had a HRAS G12C mutation. Thirty-two (36%) samples (36%) harbored TP53 mutations. Othe...

A phase II/III randomized study to compare the efficacy and safety of rigoser...

O'Neil(B H),Scott(A J),Ma(W W),Cohen(S J),... Ann Oncol 2016-06-09

...PIK3CA (1 case). No correlation between mutational status and efficacy was detected.,The combination of RIG + GEM failed...

Analysis of the molecular features of rectal carcinoid tumors to identify new...

Mitsuhashi(Kei),Yamamoto(Itaru),Kurihara(H... Oncotarget 2016-09-22

...PIK3CA or any microsatellite instability (MSI); however, we did observe CpG island methylator phenotype (CIMP) positivit...

Genomic landscape of adenoid cystic carcinoma of the breast.

Martelotto(Luciano G),De Filippo(Maria R),... J Pathol 2016-06-06

...PIK3CA and display a heterogeneous constellation of known cancer genes affected by somatic mutations, including MYB, BRA...

MicroRNA-375 functions as a tumor suppressor in osteosarcoma by targeting PIK...

Shi(Zhi-cai),Chu(Xue-rong),Wu(Yun-gang),Wu... Tumour Biol 2016-04-06

...PIK3CA was a potential target of miR-375 and it mediated reduction of PIK3CA resulted in suppression of PI3K/Akt pathway...

High mesothelin expression in advanced lung adenocarcinoma is associated with...

Thomas(Anish),Chen(Yuanbin),Steinberg(Seth... Oncotarget 2016-02-29

...PIK3CA and HER2 were assessed by pyrosequencing; HER2 amplification and ALK translocation were assessed by fluorescence ...

Genetic Alterations in Colorectal Cancer Have Different Patterns on 18F-FDG P...

Chen(Shang-Wen),Lin(Chien-Yu),Ho(Cheng-Man... Clin Nucl Med 2016-02-09

...PIK3CA. Mann-Whitney U test and logistic regression analysis were carried out for this analysis.,Genetic alterations in ...

Somatic Copy Number Abnormalities and Mutations in PI3K/AKT/mTOR Pathway Have...

Bellmunt(Joaquim),Werner(Lillian),Leow(Jef... PLoS One 2016-02-22

...PIK3CA (9%), FGFR3 (2%), HRAS/KRAS (5%), and CTNNB1 (1%). 66% of patients had some sort of CNV. PIK3CA/AKT/mTOR pathway ...

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