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Cheng(X),Qian(C),Holdridge(E),Ananda(G),Ji... bioRxiv 2026-02-17

...PIK3CA mutation, Trp53 loss, and MYC overexpression. Using this model together with human EC cell lines, patient-derived...

Brantley(KD),Kodali(A),Kirkner(GJ),Hughes(... NPJ Precis Oncol 2026-02-26

...PIK3CA (p < 0.001). OS was shorter among younger recurrent MBC patients [median: 2.8 (≤ 40) vs. 3.6 years ( > 55), p = 0...

Warwas(KM),Volckmar(AL),Kazdal(D),Ball(M),... Breast Care (Basel) 2026-05-22

...PIK3CA, PTEN, and AKT, with potential therapeutic relevance. These real-world data support the clinical utility of LBx g...

Mai(NTK),Trinh(HL),Pham(AT),Nguyen(HX),Ngu... Onco Targets Ther None

...PIK3CA mutations in 9.6%. Median PFS was 14.9 months (95% CI, 10.3-19.4), and median OS was 27.0 months (95% CI, 12.4-41...

K(AH),Harishkumar(SD),Gowda(PHS),Shivamall... Front Oncol None

...PIK3CA signaling hubs central to CRC progression. Among all screened phytochemicals, rosmarinic acid demonstrated the hi...

Wang(L),Wang(M),Li(X),Jiao(B),Song(D) Front Pediatr None

...PIK3CA-related overgrowth spectrum, is a rare vascular malformation that was first reported in 2008 and formally incorpo...

Liu(H),Guo(W),Shi(S),He(H) Beijing Da Xue Xue Bao Yi X... 2026-08-18

...PIK3CA point mutation and SETD2 deletion in one ACKD-RCC patient and the pRCC patient, which were accompanied by marked ...

Yang(Q),Lu(J),Lu(M),Hong(K) Beijing Da Xue Xue Bao Yi X... 2026-08-18

...PIK3CA gene at codon E545 (GAG>GCG), consistent with the established pathogenic mechanism underlying lymphangioma. Mecha...

Christenson(ES),Wala(JA),Parkinson(R),Coll... Nat Commun 2026-07-23

...PIK3CA inhibitor) and nivolumab (anti-PD-1) in metastatic microsatellite stable CRC (NCT03711058): Cohort A: PIK3CAwt (n...

Goto(K),Kukita(Y),Ohe(S),Hishima(T),Nishiz... Histopathology 2026-08-03

...PIK3CA hotspot mutations were detected in 8 of the 13 cases. Panel sequencing revealed KMT2D (MLL2/4) mutations in three...