...BRCA1 inhibits growth of some but not all cell lines. In an attempt to uncover the mechanism of growth suppression by BR...
...BRCA1 and in a breast cancer cell line that lacks endogenous functional BRCA1 (HCC1937). In addition, BRCA1 blocked the ...
...BRCA1 locus generates multiple protein products including BRCA1-Delta11, which is identical to the BRCA1 full-length iso...
...Brca1 wild-type and Brca1-deficient cells. The Brca1 wild-type and Brca1-deficient mouse ovarian tumors and cell lines p...
BRCA1 mediates resistance to apoptosis in response to DNA-damaging agents, causing BRCA1 wild-type tumours to be signifi...
...BRCA1 mutations (BRCA1+/mut, n=23) or without BRCA1 mutations (BRCA1+/+, n=28). BRCA1+/mut tissues showed an increased p...
...BRCA1 after ionizing radiation, indicating that PP1alpha dephosphorylates BRCA1 in vivo. BRCA1 and PP1alpha reciprocally...
...Brca1 protein. Our results demonstrate that full-length murine Brca1 is identical to human BRCA1 with respect to its cel...
...BRCA1/2 mutation carriers. Focusing on the RB1 locus, we analyzed 33 BRCA1-mutated, 36 BRCA2-mutated, and 48 non-BRCA1/2...
...BRCA1 predispose women to breast and ovarian cancers. However, the downstream mediators of BRCA1 function in tumor suppr...
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