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Assessing cardiac insufficiency risks of aflatoxin B1 through network toxicol...

Zhang(Q),Zhang(Q),Jiang(P),Zhao(X),Wen(Z),... Ecotoxicol Environ Saf 2025-10-01

...PIK3CA, NFKB1, GSK3B, TLR4, KDR, JAK2, MAPK1, PIK3R1, and PTPN11. GO and KEGG enrichment analyses demonstrated that AFB1...

Clinicopathological Analysis of a Group of Patients Diagnosed with Endometria...

Jakubowski(D),Kukla-Jakubowska(A),Michalcz... J Clin Med 2025-09-26

...PIK3CA mutations. No significant differences were observed in BMI, endometrial thickness, or abnormal bleeding between h...

GETgene-AI: a framework for prioritizing actionable cancer drug targets.

Gu(A),Chen(JY) Front Syst Biol 2025-00-00

...PIK3CA and PRKCA, validated through experimental evidence and clinical relevance. Benchmarking against GEO2R and STRING ...

Lithospermum erythrorhizon extract alleviates immunosuppression via MAPK sign...

Chi(X),Ping(L),Gai(R),Weng(Q) Front Vet Sci 2025-00-00

...Pik3ca, and Mapk1. LEE effectively ameliorates dexamethasone-induced immunosuppression by restoring immune cell activity...

Exploratory evaluation of the somatic and immunologic landscape of primary an...

Cerda(V),Rimel(BJ),Mercer(J),Thompson(MA),... Int J Gynecol Cancer 2025-12-00

...PIK3CA was the most common pathogenic somatic alteration but not statistically different across sites (q = 0.9). Molecul...

Hormone Receptor Positive/HER2 Negative Breast Carcinoma: Association of PIK3...

Lopac(D),Babarović(E),Hagen(J),Valković Zu... Int J Mol Sci 2025-09-28

...PIK3CA mutation test for the presence of PIK3CA mutation and immunohistochemistry was applied to assess PD-L1 expression...

PTEN hamartoma of soft tissue (PHOST) and fibroadipose vascular anomaly (FAVA...

Xue(S),Fu(F),Wang(Y),Liu(D),Zhu(H),Xiao(L)... Virchows Arch 2025-09-26

...PIK3CA mutations by fluorescent quantitative PCR (qPCR). Subsequently, next-generation sequencing (NGS) was performed on...

Molecular and clonal evolution of primary lesions vs. brain metastasis in EGF...

Ruíz-Patiño(A),Zuluaga(J),Wagner-Gutierrez... Transl Lung Cancer Res 2025-09-30

...PIK3CA/PTEN/AKT at 36%, BRAF (11%), and RB1 (13%) were presented. MET amplification was detected in 15% of cases upon sy...

Divergence of P53, PTEN, PI3K, Akt and mTOR expression in tonsillar cancer.

Chun(Sang Hoon),Jung(Chan-Kwon),Won(Hye Su... Head Neck 2016-01-14

...PIK3CA, Akt and mTOR.,Twenty-six patients were HPV-positive. Expression of P53 as well as PIK3CA, Akt and mTOR were not ...

PI3 Kinase in Cancer: From Biology to Clinic.

Workman(Paul),Clarke(Paul) Am Soc Clin Oncol Educ Book 2016-04-15

...PIK3CA, which encodes p110α and is the most frequently mutated kinase in the human genome. From these beginnings, there ...

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