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Identification of platelet function-related genes in STEMI patients.

Zhu(J),Yang(S),Guo(Q),Yang(Y),Shi(B) Front Genet 2025-00-00

...PIK3CA, AKT1, and PIK3R1 demonstrated strong diagnostic performance (AUC > 0.7). ROC analysis yielded the following AUC ...

Methodological Comparison of Short-Read and Long-Read Sequencing Methods on C...

Szakállas(N),Kalmár(A),Rada(KR),Kucarov(M)... Int J Mol Sci 2025-09-22

...PIK3CA, and others), we characterized platform-specific detection profiles and completed the ground truth validation of ...

USP10/GSK3β-mediated inhibition of PTEN drives resistance to PI3K inhibitors ...

Kumari(N),Wright(SC),Witham(CM),Monserrat(... J Clin Invest 2025-11-17

Activating mutations in PIK3CA, the gene encoding the catalytic p110α subunit of PI3K, are some of the most frequent gen...

A visual analysis of research hotspots and trends on macrodactyly between 200...

Liu(Y),Yang(ZY),Pang(CJ),Fan(XB),Zhao(CY),... Orphanet J Rare Dis 2025-09-24

...PIK3CA," "activating mutations," and "overgrowth" in recent years). The strongest citation burst was "overgrowth" (2016-...

Beyond BRCA deficiency: Clinical and molecular predictors of survival in pati...

Zwimpfer(TA),Fereday(S),Pandey(A),Ariyarat... medRxiv 2025-09-22

...PIK3CA or RAD21 amplification defined BRCA2-deficient HGSC with exceptionally short survival. BRCA1-deficient tumors in ...

Atractylenolide III attenuates acute kidney injury through phosphorylation of...

You(J),Sun(S),Lv(D),Fan(S),Yan(X),Liu(M),J... J Ethnopharmacol 2025-09-25

...PIK3CA were performed to confirm that ATL-III exerts its renoprotective effects through activation of the PIK3CA/AKT sig...

Identification of cytotoxic constituents from Siegesbeckiae Herba and network...

Zhang(K),Zhao(YY),Duan(XW),Xu(YB),Yao(Y),Y... Sci Rep 2025-09-26

...PIK3CA, SRC, and HRAS etc. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses indicated enri...

Congenital Vascular Anomalies: Prenatal Diagnosis, Perinatal Outcome and Post...

Faiola(S),Baraldini(V),Domenico(FD),Barrec... Prenat Diagn 2025-11-00

...PIK3CA variants were absent in amniotic fluid, even in cases that subsequently tested positive on tissue biopsy. Among t...

Assessing cardiac insufficiency risks of aflatoxin B1 through network toxicol...

Zhang(Q),Zhang(Q),Jiang(P),Zhao(X),Wen(Z),... Ecotoxicol Environ Saf 2025-10-01

...PIK3CA, NFKB1, GSK3B, TLR4, KDR, JAK2, MAPK1, PIK3R1, and PTPN11. GO and KEGG enrichment analyses demonstrated that AFB1...

Clinicopathological Analysis of a Group of Patients Diagnosed with Endometria...

Jakubowski(D),Kukla-Jakubowska(A),Michalcz... J Clin Med 2025-09-26

...PIK3CA mutations. No significant differences were observed in BMI, endometrial thickness, or abnormal bleeding between h...

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