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Kim(JJ),Walton(SA),Mahadevan(NR),Haradon(J... Clin Cancer Res 2025-09-15

...PIK3CA, RET, and FGFR3 and tumor suppressors ATM and BRCA1 (n = 1 each). Secondary genes altered in >5% of NCs included ...

Ngoi(NYL),Choi(CH),Zhu(J),Lim(D),Tan(TZ),S... Clin Cancer Res 2025-09-15

...PIK3CA mutations were associated with time to progression on durvalumab ≥12 weeks [relative risk (mutated vs. wild-type)...

Yao(S),Wei(L),Hu(Q),Liu(S),Manojlovic(Z),F... Nat Genet 2025-09-00

...PIK3CA mutations and mutational signature-based subtypes with etiologic and prognostic significance. These findings do n...

Lilja-Fischer(J),Horsholt Kristensen(M),La... Acta Oncol 2025-08-26

...PIK3CA and ATR mutations and chromosome 3q amplification. ATR and CREBBP mutations occurred more often in heavy smokers ...

Garg(V),Prokopec(SD),Stone(SC),Pakbaz(S),C... Transl Oncol 2025-11-00

...PIK3CA (33 %), and PPP2R1A (22 %). Copy-number (CN) analysis revealed recurrent amplifications of MYC (67 %), PIK3CA (61...

Kang(SW),Kang(OJ),Lee(YJ),Jung(HJ),Lee(MS)... Pract Lab Med 2025-12-00

...PIK3CA, PTEN, KRAS, and RB1, were identified in 13 patients with EOC and selected as targets for ctDNA detection. The pe...

Kübler(K),Nardone(A),Anand(S),Gurevich(D),... Nat Genet 2025-09-00

...PIK3CA mutations, common in spontaneously arising estrogen-associated de novo uterine cancer, are significantly less fre...

Hooda(J),Atkinson(JM),Shah(OS),Yates(M),Br... bioRxiv 2025-08-25

...PIK3CA (57%), CDH1 (57%) and TP53 (57%) among others. Our study confirms and characterizes new ILC PDX models, offering ...

Chan(CK),Lim(KS),Chan(CY),Kumar(TS),Audrey... Gene 2025-08-20

...PIK3CA. According to World Health Organization (WHO), at least 50 genes have been proposed as brain-tumor-related genes....

Lenz(G),Pereira(RA),Valagni(G),Biachi de C... Clin Colorectal Cancer 2025-12-00

...PIK3CA mutant tumors. These findings support biomarker-driven strategies and highlight the need for ongoing trials to va...