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Genetic profiling and pathway analysis in bladder carcinoma: Implications for...

Vasishta(S),Adiga(US),Augustine(AJ) Turk J Surg 2025-12-08

...PIK3CA, HRAS, FGFR3, and TP53 were implicated across multiple pathways. Metabolite analysis showed significant associati...

Precision oncology for advanced-stage adenocarcinoma of the appendix: compreh...

Lange(S),Lisiecki(H),Kreutzfeldt(S),Heinin... BMJ Open Gastroenterol 2025-08-21

...PIK3CA and AKT1. An elevated tumour mutational burden was identified in 26% of the tumours. A total of 74% of all patien...

Case Report: Neuroendocrine carcinoma of the breast: a review of the literatu...

Albayrak(NE) Front Med (Lausanne) 2025-00-00

...PIK3CA mutations and FGFR1 amplification, which can be of therapeutic value. The Ki-67 index, unlike in the pancreas and...

Double trouble, managing bilateral inflammatory breast cancer: a case report.

Sabaté-Ortega(J),Ribera-Montserrat(A),Del ... Front Oncol 2025-00-00

...PIK3CA mutation. Although some clinical benefit was achieved, the disease continued to progress. Ultimately, the patient...

Sex- and age- differences in the expression of critical blood-brain barrier r...

Mi(X),Ye(ZL),Zhang(XJ),Chen(XC),Dai(XM) Biol Sex Differ 2025-09-02

...Pik3ca), and some regulatory genes (Adm, Zfpm2 and Nr3c1). A similar outcome was found in the 10-month mice when compare...

Elucidating Key Components and Mechanisms Underlying the Synergistic Anti-Typ...

He(F),Su(S),Song(R),Li(Y),Zou(L),Li(Z),Xia... Antioxidants (Basel) 2025-08-29

...PIK3CA, EGFR, and MAPK1 to regulate T2DM pathways. Molecular docking confirmed strong binding affinities between these c...

Stereotactic radiosurgery for brain metastases from extra-renal clear cell ca...

Harary(PM),Hori(YS),Kattaa(AH),Lam(FC),Abu... J Clin Neurosci 2025-11-00

...PIK3CA (p.E545K) or BRCA2 (p.K3326*). Our case series indicates that SRS may be an effective management option for erCCC...

Recurrent Cellulitis in the Intergluteal Area in a Pediatric Patient with Kli...

Vera-Amaya(FD),Gomez-Restrepo(JI),Fontecha... R I Med J (2013) 2025-09-02

...PIK3CA gene, characterized classically by a triad of capillary malformations, venous malformations, and soft tissue and ...

Leveraging Real-World Data From a Clinicogenomic Database Addresses the Treat...

Ciniselli(CM),Conca(E),Bartoletti(M),Colom... JCO Precis Oncol 2025-09-00

...PIK3CA (3.9%), TP53Y220C (3.7%), ERBB2 (3.5%), CDK12 (2.3%), ARID1A (2.2%), KRAS (2.1%), and BRAF (1%) genes. Then, 439 ...

Clinical factors and molecular co-alterations impact outcomes in patients rec...

Sun(F),Banwait(MK),Singhal(S),Herrmann(A),... Lung Cancer 2025-10-00

...PIK3CA, but not TP53 alone, demonstrated significantly shorter median OS compared to the TP53 and PIK3CA wild-type popul...

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