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Mesonephric-like metaplasia of the endometrium in a woman treated with letroz...

Travaglino(A),Santoro(A),Arciuolo(D),Raffo... Pathologica 2025-09-00

...PIK3CA, RET, ROS1) showed no pathogenetic mutations. These features appear consistent with a benign endometrial mesoneph...

Unlocking the Anti-Breast Cancer Potential of Aralia chinensis L.

Xue(J),Li(L),Shu(Y),Xie(C),Lu(T),Chai(H) Curr Issues Mol Biol 2025-08-16

...PIK3CA, STAT3, and EGFR. In MCF-7 cells, TSAC suppressed proliferation and migration while downregulating Src, PI3K, and...

Circulating genomic landscape following cyclin-dependent kinase 4/6 inhibitor...

Pontolillo(L),Davis(AA),Gerratana(L),Medfo... NPJ Breast Cancer 2025-08-16

...PIK3CA (37.6%), ESR1 (46.2%) and TP53 (31.2%) were the most altered genes. Comparing with a CDK4/6i plus ET naïve contro...

UPLC-Q-TOF/MS, network pharmacology, molecular docking, and experimental vali...

Wang(T),Xia(H),Zhu(J),Yu(M),Zhang(Z),Lu(J)... Sci Rep 2025-08-16

...PIK3CA), Epidermal Growth Factor Receptor (EGFR), and Janus Kinase 2 (JAK2). Cellular tests demonstrated that resibufoge...

Comprehensive analysis of oncogenic determinants across tumor types via multi...

Ubaid(S),Kushwaha(R),Kashif(M),Singh(V) Cancer Genet 2025-11-00

...PIK3CA, as well as tumor suppressor genes like TP53, PTEN, and CDKN2A, highlighting their molecular mechanisms and roles...

Genomic and transcriptomic data reveal molecular differences between homologo...

Wang(H),Zhao(W),Zhou(W),Wang(N),Li(Y),Qin(... Hum Genomics 2025-08-31

...PIK3CA, and PTEN mutations were more common in the HRD-low group. HRD-high patients exhibited stronger immune activation...

Analysis of Oncogene Mutations in Odontogenic Myxoma.

Pankam(J),Kitkumthorn(N),Khovidhunkit(SP),... Mod Pathol 2025-12-00

...PIK3CA, and CTNNB1 primers were sent for DNA sequencing to investigate mutations in KRAS exon 2 codons 12 and 13, PIK3CA...

Potential of Amaranthus tricolor Terpenoids in Managing Obesity by Modulating...

Khandelwal(A),Pande(B),Jyotsana,Gupta(P) Cell Biochem Biophys 2025-12-00

...PIK3CA, and SRC) of the shortlisted terpenoids. Molecular docking and simulation studies of the hub genes was performed ...

Epigenetics of Endometrial Cancer: The Role of Chromatin Modifications and Me...

Piergentili(R),Marinelli(E),De Paola(L),Cu... Int J Mol Sci 2025-07-29

...PIK3CA, PIK3R1, CTNNB1, ARID1A, PPP2R1A, and FBXW7, all mutated at high frequency in EC patients. However, gene function...

NGS coverage accurately predicts MET and HER2 (ERBB2) gene amplifications in ...

Kowalewski(A),Siemanowski-Hrach(J),Stehle(... Front Oncol 2025-00-00

...PIK3CA in 9 samples, and KRAS in 9 samples, with one tumor tested for both MET and ERBB2. NGS fold changes, reflected by...

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