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Whole-genome sequencing-based characterization of endometrial serous carcinom...

Andres(S),Brown(DN),Da Cruz Paula(A),Aghaj... Gynecol Oncol 2025-10-00

...PIK3CA (60 %), FBXW7 (40 %), PPP2R1A (30 %) mutations, CCNE1 (50 %) and AKT2 amplification (30 %). All serous ECs were h...

US Food and Drug Administration Approval Summary: Inavolisib With Palbociclib...

Wedam(S),Narayan(P),Gittleman(H),Cheng(J),... J Clin Oncol 2025-10-00

...PIK3CA-mutated, hormone receptor-positive, human epidermal growth factor receptor 2 (HER2)-negative, locally advanced or...

Personalized medicine in triple-negative breast cancer: combining neoantigen ...

Martinez-Enriquez(LC),Bernal-Estévez(DA),A... Front Oncol None

...PIK3CA (p.Glu542Lys), all supported by OncoKB level-1 evidence. This case highlights the potential of integrating precis...

A Case of False-Negative Results in the One-Step Nucleic Acid Amplification A...

Koyanagi(A),Kakumoto(A),Kuroda(H),Baba(S),... Case Rep Oncol 2025-00-00

...PIK3CA, ARID1A, NF2, SETBP1, and EP300. Of these, tumor heterogeneity and genetic alterations, including mutations in AR...

Liquid biopsy in breast cancer: promises and challenges.

Loizidis(S),Stanciu(MA),Ignatiadis(M) Curr Opin Oncol 2025-09-01

...PIK3CA, ESR1, etc.). Various ctDNA assays used in randomized trials have been approved by regulatory authorities as comp...

Recurrent Cellulitis in the Intergluteal Area in a Pediatric Patient with Kli...

Vera-Amaya(FD),Gomez-Restrepo(JI),Fontecha... R I Med J (2013) 2025-09-02

...PIK3CA gene, characterized classically by a triad of capillary malformations, venous malformations, and soft tissue and ...

Sex- and age- differences in the expression of critical blood-brain barrier r...

Mi(X),Ye(ZL),Zhang(XJ),Chen(XC),Dai(XM) Biol Sex Differ 2025-09-02

...Pik3ca), and some regulatory genes (Adm, Zfpm2 and Nr3c1). A similar outcome was found in the 10-month mice when compare...

Stereotactic radiosurgery for brain metastases from extra-renal clear cell ca...

Harary(PM),Hori(YS),Kattaa(AH),Lam(FC),Abu... J Clin Neurosci 2025-11-00

...PIK3CA (p.E545K) or BRCA2 (p.K3326*). Our case series indicates that SRS may be an effective management option for erCCC...

A Case of Uterine Serous Carcinoma in a Patient with a Germline BRCA1 Mutatio...

Yamane(N),Matoba(Y),Yamazaki(T),Uyama(T),E... Case Rep Oncol 2025-00-00

...PIK3CA. BRCA1, a major causative gene of hereditary breast and ovarian cancer, may also contribute to the risk of USC. W...

Development of a machine learning model for predicting the expression of prot...

Sun(C),Li(Q),Huang(Y),Xia(Y),Li(M),Zhu(X),... Front Oncol None

...PIK3CA), and mammalian target of rapamycin (mTOR), which are frequently linked with targeted therapy for endometrial can...

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