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[Expert consensus on the clinical diagnosis and treatment of Congenital macro...

Hand Plastic Surgery Committee Aesthetic A... Zhonghua Yi Xue Yi Chuan Xu... 2025-07-10

...PIK3CA and belongs to the "PIK3CA-related overgrowth spectrum". Targeted regulation of the PI3K/AKT/mTOR pathway is beco...

Understanding and overcoming CDK4/6 inhibitor resistance in HR+/HER2- metasta...

da Silva(JL),Oliveira(LJC),de Resende(CAA)... Ther Adv Med Oncol 2025-00-00

...PIK3CA gene that activate the phosphatidylinositol 3-kinase/protein kinase B (AKT)/mammalian target of rapamycin signali...

Development of a novel PIK3CA-mutated pancreatic tumor mouse model and evalua...

Suzuki(Y),Sugimori(M),Kanemaru(Y),Onodera(... PLoS One 2025-00-00

...PIK3CAH1047R mutation, designated Ptf1acre/+; Rosa26-LSL-PIK3CAH1047R:p53loxP/loxP (PPC) mice. At 150 days of age, PPC m...

Overall Survival with Inavolisib in PIK3CA-Mutated Advanced Breast Cancer.

Jhaveri(KL),Im(SA),Saura(C),Loibl(S),Kalin... N Engl J Med 2025-07-10

...PIK3CA-mutated, hormone receptor-positive, human epidermal growth factor receptor 2 (HER2)-negative locally advanced or ...

Potential of Amaranthus tricolor Terpenoids in Managing Obesity by Modulating...

Khandelwal(A),Pande(B),Jyotsana,Gupta(P) Cell Biochem Biophys 2025-12-00

...PIK3CA, and SRC) of the shortlisted terpenoids. Molecular docking and simulation studies of the hub genes was performed ...

Epigenetics of Endometrial Cancer: The Role of Chromatin Modifications and Me...

Piergentili(R),Marinelli(E),De Paola(L),Cu... Int J Mol Sci 2025-07-29

...PIK3CA, PIK3R1, CTNNB1, ARID1A, PPP2R1A, and FBXW7, all mutated at high frequency in EC patients. However, gene function...

NGS coverage accurately predicts MET and HER2 (ERBB2) gene amplifications in ...

Kowalewski(A),Siemanowski-Hrach(J),Stehle(... Front Oncol 2025-00-00

...PIK3CA in 9 samples, and KRAS in 9 samples, with one tumor tested for both MET and ERBB2. NGS fold changes, reflected by...

Analysis of Oncogene Mutations in Odontogenic Myxoma.

Pankam(J),Kitkumthorn(N),Khovidhunkit(SP),... Mod Pathol 2025-12-00

...PIK3CA, and CTNNB1 primers were sent for DNA sequencing to investigate mutations in KRAS exon 2 codons 12 and 13, PIK3CA...

The -124C>T Mutation of the TERT Promoter Indicates Favorable Prognosis in Ov...

Zhou(X),Liu(Y),Hu(J),Zhang(J),Ren(M),Ji(G)... Curr Oncol 2025-07-27

...PIK3CA mutations were assessed by Sanger sequencing, and immunohistochemistry for ARID1A, HDAC6, Cyclin E1, and p53 was ...

Exploring the molecular mechanism of Polygonum multiflorum in treating androg...

Zhong(X),Jing(C) Medicine (Baltimore) 2025-07-04

...PIK3CA, PIK3CB, and RHOA -resveratrol, -polygonin, -chrysophanol, -rheum emodin, and -rhein were all <-9 kcal/mol. PM's ...

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