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Zeng(J),Li(Q),Li(K),Yang(L),Xu(L),Wang(W),... Front Immunol 2025-00-00

...PIK3CA (47.1%) and SPOP (23.5%), but their functions were mutually exclusive. In addition, pathways and genes associated...

Ochman(B),Kot(A),Mielcarska(S),Kula(A),Daw... Int J Mol Sci 2025-07-14

...PIK3CA-mutated tumors (p < 0.05), while no associations were found with KRAS, NRAS, BRAF, AKT1, or MSI status. Multiplex...

Chen(J),Yu(H),Lin(Y),Hu(D),Liu(L),Fan(R),Z... Front Immunol 2025-00-00

...PIK3CA, highlighting the importance of the PI3K-AKT pathway in the antitumor mechanism of cadonilimab. Cadonilimab shows...

Mousavikia(SN),M Matin(M),Bahreyni Tossi(M... BMC Cancer 2025-07-14

...PIK3CA, with remarkable changes in gene expression after irradiation. Transfection and irradiation decreased cell surviv...

Yoon(CE),Kang(S),Rhew(SA),Kwon(HJ),Shin(D)... BMC Urol 2025-07-14

...PIK3CA, LRP6, LRRK2, and APOBEC3B deletion. BRCA2, BCL6, and CHEK2 were significant predictors for BCR. CONCLUSION: Our ...

Kubota(A),Bandoh(N),Goto(T),Kono(M),Sato(R... Mol Clin Oncol 2025-10-00

...PIK3CA in 2 (8%) of these 24 patients. Multivariate Cox proportional hazard analysis revealed that PIK3CA mutation was a...

Khalifa(M),Hmed(AA),Elfeky(KS),Bakry(S),Ha... J Genet Eng Biotechnol 2025-09-00

...PIK3CA. The present study represents the first comprehensive somatic mutation profile in HCC Egyptian patients. This fin...

Arabshomali(A),Goswami(S),Masurkar(PP) Am J Clin Oncol 2025-10-01

...PIK3CA gene. A literature review was conducted to evaluate the safety and efficacy of inavolisib in breast cancer. Studi...

Heidrich(I),Rautmann(C),Ly(C),Khatri(R),Kö... J Exp Clin Cancer Res 2025-07-12

...PIK3CA variants. Overall tissue-plasma concordance was 51.6%, with more extended biopsy-plasma intervals associated with...

Chowdhury(T),Tesileanu(CMS),Kocakavuk(E),J... bioRxiv 2025-07-15

...PIK3CA , PIK3R1 , and NOTCH1 were newly acquired in recurrent oligodendrogliomas and associated with increased mutation ...