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RhoB regulates prostate cancer cell proliferation and docetaxel sensitivity via…

Sheng(T),Su(H),Yao(L),Qu(Z),Liu(H),Shao(W),Z… BMC Cancer 2025-02-26

...RhoB's function in prostate cancer, CRISPR/Cas9 gene editing technique was utilized to knock out the RhoB gene in prosta...

Regulation of RhoB Gene Expression during Tumorigenesis and Aging Process and I…

Gutierrez(E),Cahatol(I),Bailey(CAR),Lafargue… Cancers (Basel) 2019-06-13

...RhoB and tumorigenesis within the context of age-related decline in RhoB. RhoB appears to play a tissue-specific role in...

RhoB alteration is necessary for apoptotic and antineoplastic responses to farn…

Liu(Ax),Du(W),Liu(JP),Jessell(TM),Prendergas… Mol Cell Biol 2000-08-00

...RhoB isoform (RhoB-GG) that occurs due to modification of RhoB by geranylgeranyltransferase I in drug-treated cells. Not...

TRIF-GEFH1-RhoB pathway is involved in MHCII expression on dendritic cells that…

Kamon(H),Kawabe(T),Kitamura(H),Lee(J),Kamimu… EMBO J 2006-09-06

...RhoB colocalized with MHCII+ lysosomes in DC. A dominant-negative (DN) form of RhoB (DN-RhoB) or RhoB's RNAi in DC inhib...

Advances in Understanding How RhoB Regulates Akt Inhibition Efficacy in NSCLC.

Akgun(N),Halici(Z),Cadirci(E) Curr Cancer Drug Targets 2025-01-16

...RhoB in A549 cells using siRNA. According to the results of the 72-hour experiment, RhoB upregulation was observed to re...

Regulation of myosin light chain phosphorylation by RhoB in neuronal cells.

Conway(AM),James(AB),O'Kane(EM),Rakhit(S),Mo… Exp Cell Res 2004-10-15

...RhoB, and not RhoA, is activated in neurones by high-frequency stimulation. However, the downstream consequences of RhoB...

Farnesylated RhoB prevents cell cycle arrest and actin cytoskeleton disruption …

Allal(C),Pradines(A),Hamilton(AD),Sebti(SM),… Cell Cycle 2002-00-00

...RhoB pathway and disrupts stress fiber and focal adhesion formation in NIH-3T3 cells. Farnesylated (V14)RhoB-CAIM (resis...

[Improved therapeutic effectiveness by combining recombinant human RhoB with lo…

Hu(XH),Wu(WF),Qing(Y),Song(LF),Huang(W),Wu(Y… Sichuan Da Xue Xue Bao Yi Xue… 2011-07-00

...RhoB with low-dose cisplatin in lung carcinoma models. The pVITRO2-RhoB recombinant was constructed and transfected into...

Loss of RhoB expression enhances the myelodysplastic phenotype of mammalian dia…

DeWard(AD),Leali(K),West(RA),Prendergast(GC)… PLoS One 2009-09-21

...RhoB(-/-) mice relative to Drf1(-/-)RhoB(+/-) mice. These data suggest a role for RhoB-regulated mDia1 in the regulation...

Cell growth inhibition by farnesyltransferase inhibitors is mediated by gain of…

Du(W),Lebowitz(PF),Prendergast(GC) Mol Cell Biol 1999-03-00

...RhoB but a gain of geranylgeranylated RhoB (RhoB-GG), which is associated with loss of growth-promoting activity. In thi...

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