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Transcriptional repression of BRCA1 by aberrant cytosine methylation, histone...

Rice(J C),Futscher(B W) Nucleic Acids Res 2000-10-30

...BRCA1 promoter compared to non-methylated BRCA1 expressing cells. The chromatin of the methylated UACC3199 BRCA1 promote...

Novel consensus DNA-binding sequence for BRCA1 protein complexes.

Cable(P LouAnn),Wilson(Cindy A),Calzone(Fr... Mol Carcinog 2003-10-29

...BRCA1 function in sporadic breast cancers that do not involve germline BRCA1 mutations. The functional specificity of BR...

BRCA1 mutation analysis of 41 human breast cancer cell lines reveals three ne...

Elstrodt(Fons),Hollestelle(Antoinette),Nag... Cancer Res 2006-02-23

...BRCA1 mutants expressed nuclear BRCA1 proteins as detected with Ab-1 and Ab-2 anti-BRCA1 monoclonal antibodies. These th...

BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival...

Gorrini(Chiara),Baniasadi(Pegah S),Harris(... J Exp Med 2013-10-01

...BRCA1 in regulating oxidative stress, but the molecular mechanism and the impact in BRCA1-associated tumorigenesis remai...

Effect of BRCA1 on epidermal growth factor receptor in ovarian cancer.

Li(Da),Bi(Fang-Fang),Cao(Ji-Min),Cao(Chen)... J Exp Clin Cancer Res 2014-09-26

...BRCA1-mutated or not, 23 pairs of BRCA2-mutated or not, and 22 pairs with hypermethylated BRCA1 promoter or not). BRCA1 ...

Large BRCA1 and BRCA2 genomic rearrangements in Danish high risk breast-ovari...

Hansen(Thomas v O),Jønson(Lars),Albrechtse... Breast Cancer Res Treat 2009-07-29

...BRCA1 exon 5-7 deletion with a novel breakpoint, a BRCA1 exon 13 duplication, a BRCA1 exon 17-19 deletion, a BRCA1 exon ...

BARD1 induces BRCA1 intranuclear foci formation by increasing RING-dependent ...

Fabbro(Megan),Rodriguez(Jose A),Baer(Richa... J Biol Chem 2002-07-25

...BRCA1, implicating BARD1 in nuclear targeting of BRCA1 for DNA repair. Our identification of BARD1 as a BRCA1 nuclear ch...

BRCA1 wild-type allele modifies risk of ovarian cancer in carriers of BRCA1 g...

Ginolhac(Sophie M),Gad(Sophie),Corbex(Mari... Cancer Epidemiol Biomarkers... 2003-05-30

...BRCA1 germ-line mutations. We found that BRCA1 carriers with the wild-type BRCA1 copy bearing a common Gly1038 variant w...

BRCA1 interaction with human papillomavirus oncoproteins.

Zhang(Yiyu),Fan(Saijun),Meng(Qinghui),Ma(Y... J Biol Chem 2005-11-30

...BRCA1 and reduced their ability to rescue BRCA1 inhibition of ER-alpha. E6 and E7 also antagonized the ability of BRCA1 ...

BARD1 regulates BRCA1 apoptotic function by a mechanism involving nuclear ret...

Fabbro(Megan),Schuechner(Stefan),Au(Wendy ... Exp Cell Res 2004-10-04

...BRCA1-induced apoptosis was independent of p53 and was stimulated by BRCA1 nuclear export. Conversely, BARD1 reduced BRC...

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