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Gupta(H),Brantley(KD),Grinda(T),Freedman(R... ESMO Open 2026-09-14

...PIK3CA (44%), TP53 (33%), CDH1 (22%) and amplifications in CCND1 (18%). After adjustment, older age was associated with ...

Brenna(D),Puglisi(M),Epistolio(S),Barizzi(... Int J Mol Sci 2026-09-01

...PIK3CA, and AR amplification. IT-HPV seems to be infrequent in metastatic and locally advanced PCa in Western population...

Ottaiano(A),Picone(C),Santorsola(M),Berret... Cancers (Basel) 2026-08-28

PIK3CA, which encodes the p110α catalytic subunit of phosphoinositide 3-kinase (PI3K), is one of the most frequently alt...

Liu(X),Chen(Y),Han(W),Chen(Y),Feng(W),Zhou... Annu Rev Pharmacol Toxicol 2026-01-00

...PIK3CA mutations (e.g., H1047R, E542K, and E545K), is a hallmark of many cancers. Advances in structural, biochemical, a...

Cui(K),Zhu(R),Li(J) Front Genet 2026-00-00

...PIK3CA (7.0%), transformation to small cell lung cancer (9.3%), and epithelial-mesenchymal transition (12.8%). Concurren...

Heidrich(I),Streckenbach(A),Rautmann(C),Fr... J Transl Med 2026-09-17

...PIK3CA. We paired ctDNA measurements with radiologic staging and correlated them with response categories (n = 99 time p...

Xu(Y),Zhou(J),Lan(Y),Ji(Y) Br J Dermatol 2026-09-17

...PIK3CA mutations in lymphatic and venous malformations, KRAS/MAP2K1 mutations in arteriovenous malformations, and cerebr...

Voutsadakis(IA) Mol Diagn Ther 2026-01-00

...PIK3CA gene mutations, PI3K inhibitors have met with limited success, and development has mostly been halted or stagnate...

Zhao(Y),Ma(Y),Xiong(L),Ai(J),Wang(X),Chen(... J Ethnopharmacol 2026-01-30

...PIK3CA, and MAPK3 related to autophagy would be the core targets for the active compounds of CR-CC. Further studies show...

Huang(QS),Yu(XZ),Zhao(R),Huang(LB),Wen(J),... Int J Surg 2026-01-01

...PIK3CA mutation rates (OR: 0.93; 95% CI: 0.88-0.99; P = 0.03). EOCRC and LOCRC had similar 5-year OS rates (HR: 1.01; 95...