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Khan(MR),Akram(R),Luqman(A),Ullah(R),Ullah... J Ethnopharmacol 2026-09-12

...PIK3CA, and HRAS as core target proteins. GO and KEGG enrichment analysis revealed PI3K/AKT, JAK/STAT signaling, inflamm...

Pang(C),Lee(R),Nisbet(R),Hamilton(G),Brook... Phlebology 2026-04-00

...PIK3CA) inhibitors, and AKT inhibitors are being developed to target the Phosphoinositide 3-Kinase (PI3K)/AKT/mTOR pathw...

Agostini-Vulaj(D),Oltavi(ZN),Liao(X) Virchows Arch 2026-04-00

...PIK3CA (43%) and APC (29%). The morules harbored similar or more pathogenic mutations compared to the background neoplas...

Ries(AG),Barry(KK),Thiessen(A),Plunk(MR),K... Pediatr Dermatol 2026-00-00

...PIK3CA variants are well-documented and are classified within the PIK3CA-related overgrowth spectrum (PROS), yet PIK3CA-...

Jeong(H),Oh(JH),Ahn(HS),Ryoo(BY),Kim(KP),J... J Hepatol 2026-01-00

...PIK3CA and FBXW7 mutations were significantly associated with poor DFS, and 11q13.3 amplification with favorable DFS. So...

Zhu(Z),Yuan(SM) Pediatr Blood Cancer 2026-09-16

The PIK3CA-related overgrowth spectrum (PROS) encompasses a group of rare, somatic disorders caused by somatic activatin...

Mao(X),Ma(K),Wang(Y),Long(C),Tan(X),Chen(X... Virchows Arch 2026-08-00

...PIK3CA (55.0%) mutations being predominant. Comparative analysis revealed ethnic variations, with higher NF1 mutation fr...

Li(W),Liu(M),Wu(L),Zhu(B),Li(X),Yang(Z),Li... Clin Transl Oncol 2026-03-00

...PIK3CA (24.56%), and SMAD4 (24.56%). Pathway analysis revealed significant enrichment in p53, IGF, and Ras signaling pat...

Shaikh(S),Akbar(A),Khalifey(HT),Raziq(T),A... Front Oncol 2026-00-00

...PIK3CA for roughly 10% of curated somatic mutation records pooled across 44 studies (proportions of mutation calls, not ...

Othman(NS),Aminuddin(A),Hamid(AA),Abidin(S... Int J Mol Sci 2026-08-24

...PIK3CA as a biologically plausible candidate target for further investigation. This study investigated the functional si...