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Yizhi Dihuang Decoction Ameliorates Mild Cognitive Impairment by Restoring Au...

Hao(Z),Meng(T),Li(S),Bu(Y),Qie(R),Chen(J) Rejuvenation Res 2026-07-09

...PIK3CA, PIK3CD, and mTOR; docking supported feasible engagement. In vivo, YZDHD improved spatial learning and recognitio...

PFKP promotes oncogenesis in osteosarcoma through PI3K/HIF-1α pathway-mediate...

Zhang(X),Guan(M),Wang(Y),Ding(C),Yu(X),Shi... Cell Signal 2026-11-00

...PIK3CA and HIF1A. Furthermore, through analysis of the HERB and CTD databases and molecular docking simulations, we unco...

Somatic Mutation Profiles in Colorectal Cancers Differ by Population.

Mabvakure(BM),Promprasert(P),Martinez Cruz... medRxiv 2026-06-29

...PIK3CA, and TP53 , as well as in pathogenic variant occurrence. Geographic origin and age of onset appear to shape the C...

Beyond Lesion Control: A Narrative Review of Targeted Therapy and Surgical De...

Altamimi(O),Altamimi(I),Alhowidi(R),Alosai... Cureus 2026-06-00

...PIK3CA-related overgrowth spectrum and selected vascular malformations, has shifted the management paradigm. These agent...

Endophytic Aspergillus glaucus as a novel epothilone B producer: Antiprolifer...

El-Sayed(ASA),Refaat(S),El-Sayed(MA),Fikry... Appl Microbiol Biotechnol 2026-07-10

...PIK3CA, mTOR, and HSP90, in addition to binding the β-tubulin taxane site, highlighting its capacity to modulate multipl...

Frequent Detection of KRAS-G12C and PIK3CA-Q546K Mutations in MAP Tumors High...

Medeiros(ABD),Kozak(VN),Picanço-Albuquerqu... Hum Mutat None

...PIK3CA-Q546K are highly enriched in MAP CRCs, and are rarely observed in sporadic cases, suggesting their potential util...

Variant allele frequency as a potential marker in response to frontline syste...

Jang(A),Wu(S),Kumar(HLS),Kyasaram(RK),Cala... Transl Androl Urol 2026-04-27

...PIK3CA, with no statistical difference in any alteration frequency between the cohorts. Amongst patients with sustained ...

Single-nucleotide variant profiling in liquid biopsy with RECO-Cas.

Guo(C),Zhang(S),Yerramsetti(R),Zhang(J),Gu... Sci Adv 2026-05-22

...PIK3CA point mutations in cfDNA from clinical plasma samples, demonstrating high sensitivity (90.48%) and excellent spec...

Somatic mutation profiling by NGS-based liquid biopsy in advanced non-small c...

Doğan(Ç),Akosman(C),Sönmez(M),Yılmaz(B),De... Mol Biol Rep 2026-05-23

...PIK3CA (14.5%). Multimetastatic patients had significantly higher cfDNA levels (10.0 ± 3.9 vs. 3.8 ± 1.0 ng; p = 0.01) a...

Distinct subtypes of kidney transplant-associated urothelial carcinomas harbo...

Wang(JW),Li(YJ),Huang(TH),Wu(HH),Wang(HH),... Biomed J 2026-05-23

...PIK3CA (16%), FGFR3 (11%), HRAS (11%)]. Notably, UC specimens with BKPyV integration harbored significantly fewer mutati...

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