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Knöpfel(N),Barberan-Martin(S),Polubothu(S)... Br J Dermatol 2026-04-17

...PIK3CA and GNA11, alongside further cases of mosaic GNAQ. The HRAS variant has previously been reported in the germline ...

Oliveira(M),Ciruelos(E),Villacampa(G),Mora... Clin Cancer Res 2026-02-04

...PIK3CA mutations (PIK3CAmut). This prospective, multicenter, single-arm, phase Ib study evaluated the safety and prelimi...

Han(R),Wang(S),Zhou(Z),Huang(D),Hou(J),Tia... Exp Cell Res 2026-01-15

...PIK3CAH1047L mutation. Consistent with this, bioinformatics analysis demonstrated that miR-124-3p expression is signific...

Karmakar(V),Majie(A),Ghosh(A),Deb(PK),Gora... ACS Chem Neurosci 2026-01-07

...PIK3CA, and PIK3CB. Molecular dynamics simulations further confirmed the stability and favorable interactions of azilsar...

Krings(G),Bean(GR),Hosfield(EM),Rowe(JJ),G... Mod Pathol 2026-03-00

...PIK3CA, CDKN2A/B, LZTR1, KMT2B, and ARID2 (1 case each). Low-grade PDST, which lacked marked pleomorphism, high mitotic ...

Jha(S),Lobo(A),Sangoi(AR),Kandukuri(SR),Mi... Histopathology 2026-05-00

...PIK3CA and KRAS mutations, while the remaining tumours had either isolated PIK3CA alterations or co-occurring loss-of-fu...

Mao(H),Li(Z),Lu(C) Braz J Med Biol Res None

...PIK3CA upregulation. Mechanistically, silencing PIK3CA in rat H9c2 cardiomyoblasts diminished the beneficial effects aga...

Chawapun(P),Khamto(N),Halimi(YF),Utama(K),... Bioorg Chem 2026-03-00

...PIK3CA, potentially influencing apoptosis via the PI3K/AKT pathway. The compound 2j significantly inhibited the MDA-MB-2...

Wang(F),Wang(Y),Wang(Q),Liu(Y),Rashid(HU),... J Pharm Pharmacol 2026-01-16

...PIK3CA, AKT1, HSP90AA1, and STAT3 as core targets. KEGG pathway analysis further highlighted PI3K-AKT, MAPK, HIF-1, and ...

Alfieri(S),Rota(S),Romanò(R),Capone(I),Bus... ESMO Open 2026-02-00

...PIK3CA (18%), HRAS (14%) and PTEN (5%), in the absence of gene fusions. We found P-LPV in 50% of LA non-AdCCs (37/253, 1...