...PIK3CA-mutant metastatic colorectal cancer who had progressed after standard chemotherapy. Patients received oral alpeli...
...PIK3CA were observed in 60% of cases. Additionally, one patient had high TMB status. Given the challenges in diagnosis a...
...PIK3CA (22%) across tumor regions. Shared truncal mutations and copy-number alterations between ACC and SCCC regions sug...
...Pik3ca in muscle, accompanied by upregulation of PPARα and CPT1a and downregulation of FASN and ACC1 in the liver. Furth...
...PIK3CA and TEK). They remain poorly documented and frequently misclassified due to persistent outdated terminology and d...
...PIK3CA alterations, exhibited primary resistance to afatinib with radiographic progression after one month. She subseque...
...PIK3CA, FYN, PTK2, SRC, PTPN11, PIK3R1, CTNNB1, and AKT1, indicating a critical role for kinase-driven vascular signalli...
...PIK3CA. In the multivariable Cox regression model, postoperative adjuvant radiotherapy (RT + TMZ) emerged as the sole in...
...PIK3CA, ATM, and CTNNB1 and loss of CDKN2A/B, MLH1, and BAP1. To resolve this uncertainty, the EGFR mutations were recre...
...PIK3CA) were identified. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses revealed signifi...
山东省济南市章丘区文博路2号
齐鲁师范学院 genelibs生信实验室
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