...Pik3ca, Bcl2l11, Gadd45a, Pmaip1, Ddit3, and Fos), and the p53 signaling pathway (Serpine1, Sesn2, Ccng2, Igf1, Mdm2, Ga...
...PIK3CA mRNA levels predicted inferior survival in external cohorts. p110α protein expression is an independent biomarker...
...PIK3CA in oncogenesis, where TP53 is inhibited through disruptive loss-of-function mutations, whereas PIK3CA is recurren...
...PIK3CA/AKT1 mutations (n = 104). Both TIGIT and CD155 were significantly elevated in tumor tissue versus margins (p < 0....
...PIK3CA mutations were observed. Patients experiencing relapse more than six months after diagnosis were more likely to h...
...PIK3CA (25.5%), TP53 (21.6%), ARID1A (20.6%), and KRAS (16.7%). Significant amplification of ERBB2 was also observed (n ...
PIK3CA mutations drive benign adipose overgrowth in facial infiltrating lipomatosis (FIL), but the downstream molecular ...
...PIK3CA, MUC17, MAP3K4, MUC2, BRAF, NF1). Genetic landscapes were similar in SDT iCCA with and without BDTT; recurrent mu...
...PIK3CA mutations were the second most common, detected in 11.6%, 4.5%, and 5.8% of patients, respectively. ctDNA positiv...
...PIK3CA mutations and dMMR/MSI-H were increased in females. Our study queries one of the largest datasets of GI- and P-NE...
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