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Osimertinib plus anlotinib in untreated, EGFR-mutated, advanced non-small-cel...

Yang(X),Tan(Q),Chen(S),Xie(J),Zeng(Y),Zhen... Oncologist 2026-08-27

...PIK3CA, or RB1, who had not undergone systemic treatment. Kaplan-Meier survival analysis tested the differences among pa...

STK11 Mutations and Deletions Define an Aggressive Molecular Subgroup of Cerv...

Robinson(EW),Murphy(EA),Albanez(A),Tulsyan... Cancer Med 2026-09-00

...PIK3CA mutation. Cervical adenocarcinomas also demonstrated significantly lower CD274 (PD-L1) expression than SCC. STK11...

The mechanism of malignant progression in extramammary Paget's disease (EMPD)...

Kajihara(I) Med Mol Morphol 2026-09-10

...PIK3CA are detected. Tumor evolution in EMPD is characterized by high genetic intratumor heterogeneity with shared backg...

Alpinia Oxyphylla-Shenqi Siwu Decoction protects against high glucose-induced...

Zhang(W),Jing(C) Int Ophthalmol 2026-09-10

...PIK3CA, AKT1, mTOR, Caspase-3, Bcl-2 and Bax were quantified by CCK-8 assay, scratch assay, flow cytometry, DCFH-DA stai...

Comprehensive Genomic Profiling of Sinonasal Carcinomas: Identification of Co...

Bitar(G),Hsia(B),Alshaka(S),Valencia(BA),K... J Neurol Surg B Skull Base 2026-06-00

...PIK3CA ( p  = 0.018). TP53, PIK3CA, and KMT2D mutations are prevalent in sinonasal carcinoma, highlighting potential tar...

HER3 Expression and PIK3CA Mutational Status Predict Pathological Response of...

Xia(X),Zong(Z),Shen(J),Zhou(L),Lei(Y),Li(J... Cancer Res Treat 2026-07-00

...PIK3CA mutation for the efficacy of neoadjuvant therapy in human epidermal growth factor receptor 2 (HER2)-positive brea...

Mechanisms of acquired resistance to osimertinib in EGFR T790M-Positive lung ...

Cui(K),Zhu(R),Li(J) Front Genet 2026-00-00

...PIK3CA (7.0%), transformation to small cell lung cancer (9.3%), and epithelial-mesenchymal transition (12.8%). Concurren...

Encapsulated Papillary Carcinoma of the Breast: Two Cases with Literature Rev...

Baboli(KM),Salehiazar(S),Tran(T) R I Med J (2013) 2026-02-02

...PIK3CA gene. This report underscores the importance of integrating clinical, histological, and molecular findings to gui...

Biomarkers for Predicting Malignant Transformation of Premalignant Lesions of...

Rodrigo(JP),de Lima-Souza(RA),López(F),Ste... Diagnostics (Basel) 2026-01-12

...PIK3CA amplification and mutations, FGFR3 mutations). Five studies provided adequate follow-up data on transformation ou...

Lung Cancer in Never-Smokers: Risk Factors, Driver Mutations, and Therapeutic...

Chen(PM),Huang(YH),Li(CY) Diagnostics (Basel) 2026-01-12

...PIK3CA, OS9, MET, and STK11 mutations are characteristic of never-smokers, in contrast to TP53 mutations, which are more...

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