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Geranylgeranylated RhoB is sufficient to mediate tissue-specific suppression of…

Liu(A),Prendergast(GC) FEBS Lett 2000-09-22

...RhoB (RhoB-GG) in cells. However, the mechanism by which RhoB-GG acts is unclear. Here we report that RhoB-GG is suffici...

RhoB Acts as a Tumor Suppressor That Inhibits Malignancy of Clear Cell Renal Ce…

Chen(W),Niu(S),Ma(X),Zhang(P),Gao(Y),Fan(Y),… PLoS One 2016-00-00

...RhoB in clear cell renal cell carcinoma (ccRCC). The expression of RhoB was examined in specimens of patients and cell l...

RhoB regulates the function of macrophages in the hypoxia-induced inflammatory …

Huang(G),Su(J),Zhang(M),Jin(Y),Wang(Y),Zhou(… Cell Mol Immunol 2017-03-00

...RhoB and the mechanism and significance of RhoB expression in macrophages. We found that hypoxia significantly upregulat...

RhoB in cancer suppression.

Huang(M),Prendergast(GC) Histol Histopathol 2006-00-00

RhoB is a mainly endosomal small GTPase that regulates actin organization and vesicle trafficking. Expression of RhoB is...

Ras-related GTPase Rhob represses NF-kappaB signaling.

Fritz(G),Kaina(B) J Biol Chem 2001-02-02

...RhoB on signal pathways that are rapidly evoked by genotoxic compounds. The data obtained show that wild-type RhoB neith...

ATR/Chk1 signaling induces autophagy through sumoylated RhoB-mediated lysosomal…

Liu(M),Zeng(T),Zhang(X),Liu(C),Wu(Z),Yao(L),… Nat Commun 2018-00-08

...RhoB by Chk1. Phosphorylation of RhoB enhances its interaction with the TSC2, and promotes its sumoylation by PIAS1, whi...

RhoB controls Akt trafficking and stage-specific survival of endothelial cells …

Adini(I),Rabinovitz(I),Sun(JF),Prendergast(G… Genes Dev 2003-11-01

...RhoB, in vascular development. RhoB null mice have retarded vascular development in the retina characterized by altered ...

RhoB prenylation is driven by the three carboxyl-terminal amino acids of the pr…

Baron(R),Fourcade(E),Lajoie-Mazenc(I),Allal(… Proc Natl Acad Sci U S A 2000-10-10

...RhoB prenylation appear more complex than initially thought. To determine the role of RhoB CAAX motif, we designed RhoB ...

A role for RhoB in synaptic plasticity and the regulation of neuronal morpholog…

McNair(K),Spike(R),Guilding(C),Prendergast(G… J Neurosci 2010-03-03

...RhoB has been relatively neglected. We previously demonstrated that LTP is associated with specific RhoB activation. Her...

RhoB determines tumor aggressiveness in a murine EGFRL858R-induced adenocarcino…

Calvayrac(O),Pradines(A),Raymond-Letron(I),R… Clin Cancer Res 2014-12-15

...RhoB expression has been suggested to be critical for lung cancer invasion. Here, we tested RhoB expression as a prognos...

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