...PIK3CA, and TP53, on tumor progression and highlight their dynamic interactions with the TME, which can modulate, mask, ...
...PIK3CA), AKT serine/threonine kinase 3 (AKT3), and integrin subunit β1 (ITGB1). Importantly, the enhanced protein transl...
...PIK3CA/AKT1/PTEN alterations, and CD73, with a trend for improved activity in the PD-L1-positive subgroups. These findin...
...PIK3CA alterations demonstrated a median PFS of 5.3 (3.6-7.4) and 4.7 (3.6-6.7) months, respectively. This meta-analysis...
...PIK3CA and ESR1, germline/somatic BRCA1/2, and PD-L1 expression. Furthermore, liquid biopsy, particularly the analysis o...
...PIK3CA, are mutated in up to 32%, 15%, and 11% of localized prostate tumors, respectively. We aimed to further character...
...PIK3CA, AKT, Bax, and Bcl-2, providing supportive in silico evidence for its potential modulation of EGFR/PI3K/AKT signa...
...PIK3CA-mutated breast cancer and represents a promising strategy in gynecologic tumors with aberrant PI3K/AKT/mTOR pathw...
...PIK3CA, AKT1, or PTEN alterations. Drug combination approaches with paclitaxel or olaparib have demonstrated additive or...
...PIK3CA-which serve as key regulators in CKD pathophysiology. Gene Ontology and KEGG pathway enrichment analyses indicate...
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