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Cox(David G),Simard(Jacques),Sinnett(Danie... Hum Mol Genet 2012-02-22

...BRCA1 gene would modify the risk of breast cancer in carriers of BRCA1 mutations. A total of 9874 BRCA1 mutation carrier...

Yamashita(Nami),Tokunaga(Eriko),Kitao(Hiro... Clin Breast Cancer 2016-08-31

...BRCA1 mRNA expression (P < .0001), and loss of BRCA1 protein expression (P = .0015). BRCA1 promoter methylation was sign...

Shao(N),Chai(Y L),Shyam(E),Reddy(P),Rao(V ... Oncogene 1996-09-04

...BRCA1. The expression of BRCA1 protein in the BRCA1 transfectants were analysed by immunofluorescence and immunohistoche...

Zheng(L),Li(S),Boyer(T G),Lee(W H) Oncogene 2001-02-01

BRCA1 and BRCA2 are breast cancer susceptibility genes. Mutations within BRCA1 and BRCA1 are responsible for most famili...

Lee(J S),Collins(K M),Brown(A L),Lee(C H),... Nature 2000-04-07

...BRCA1 function after DNA damage by phosphorylating serine 988 of BRCA1. We show that hCds1 and BRCA1 interact and co-loc...

Hsu(Lih-Ching) Biochem Biophys Res Commun 2007-08-23

...BRCA1 phosphorylation. Unlike wild-type BRCA1, expression of the PP1 non-binding mutant BRCA1 protein in BRCA1-deficient...

Jia(Y),Song(W),Zhang(F),Yan(J),Yang(Q) Oncogene 2013-06-19

...Brca1 deficiency. Here, we show that Akt1 promotes chromosome instability in Brca1-deficent cells. DNA breaks in Brca1-d...

Magdinier(F),Dalla Venezia(N),Lenoir(G M),... Oncogene 1999-08-17

...BRCA1 are associated with elevated risk of breast cancer. Evidence for the involvement of Brca1 in cellular differentiat...

Sato(Ko),Hayami(Ryosuke),Wu(Wenwen),Nishik... J Biol Chem 2004-09-21

...BRCA1-BARD1 both identified NPM. NPM interacts with N-terminal fragments of BRCA1 and BARD1 in a manner dependent upon B...

Liu(Weijun),Zong(Wenjun),Wu(George),Fujita... PLoS One 2011-07-05

...BRCA1) increase the susceptibility to tumorigenesis. The function of BRCA1 is to regulate critical cellular processes, i...