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Exploring the Therapeutic Potential of Ganoderic Acid A Against Inflammatory ...

Cai(M),Sun(M),Li(K),Wang(Z),Mao(J),Sha(R) Int J Mol Sci 2026-06-24

...PIK3CA), and Caspase 3 (CASP3). Molecular docking confirmed high-affinity binding of GAA to these targets, with binding ...

Genomic Variability of the HCT116 Cell Line Identified Using Oxford Nanopore ...

Mikheeva(R),Leonov(P),Koryukov(M),Ruleva(E... Int J Mol Sci 2026-06-26

...PIK3CA, MLH1, CTNNB1, CDKN2A, TGFBR2, and BRCA2. However, its landscape of large genomic rearrangements (LGRs) and copy ...

Morphologic, Immunohistochemical, and Molecular Features of Laser-Ablated Thy...

Tralongo(P),Russotto(F),Zuccalà(V),Fiorent... Int J Mol Sci 2026-06-30

...PIK3CA alterations, and RET rearrangements, was performed using targeted next-generation sequencing. All nodules showed ...

Investigating the Potential Mechanism of Oxymatrine in Alleviating Heat Stres...

Cheng(S),Song(X),Qiu(W),Liu(X),Peng(G),Xin(J) Int J Mol Sci 2026-06-30

...PIK3CA and GSK3B, with Vina scores below -8 kcal/mol. In 293T cells, the half-maximal cytotoxic concentration (CC50) of ...

Antioxidant Activity of Ethanolic Litchi chinensis Seed Extract in Oxidative ...

Zhang(L),Tang(A),Yang(Z),Li(W) Molecules 2026-06-25

...PIK3CA, ERBB2 and proto-oncogene tyrosine-protein kinase Src (SRC) were screened using network pharmacology, among which...

Promoter Methylation and Somatic Mutations in Cancer-Related Genes Are Associ...

Deligonul(A),Sarimahmut(M),Sahin(AB),Ertur... J Clin Med 2026-06-30

...PIK3CA, BAP1, PTEN, and TP53. Next-generation sequencing (NGS) with an 86-gene pan-cancer panel was conducted on 9 HPD s...

Case Report: Synchronous minute intramucosal Epstein-Barr virus-associated ga...

Wu(D),Luo(Q),Wang(W),Wang(X) Front Med (Lausanne) None

...PIK3CA mutations, and high PD-L1/PD-L2 expression. We report the case of a 56-year-old patient diagnosed with gastric ad...

Coexisting driver alterations in non-small cell lung cancer: Prevalence, clon...

Shah(R),Pathak(GP),Fris(J),Castonguay(M),G... Eur J Cancer 2026-09-09

...PIK3CA or EGFR + PIK3CA co-mutations did not impact prognosis in early-stage but was associated with worse outcomes in a...

Core genes drive treatment resistance in triple-negative breast cancer: chara...

Zhang(ZX),Zhao(W),Xiao(YX),Shen(XL),Ming(M... Biochem Pharmacol 2026-10-00

...PIK3CA, and CDK4/6, we discovered that they promote tumor growth and metastasis by abnormally activating the Notch, Wnt/...

Investigation of Oncogenic Gene Mutation and Associated Protein Expression in...

Lapthanasupkul(P),Pankam(J),Khovidhunkit(S... Oral Dis 2026-07-15

This study aimed to investigate gene mutations in ameloblastic carcinoma (AC) including BRAF, KRAS, and PIK3CA, along wi...

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