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Remodeling the gut-heart axis: Danggui Sini granule mitigates vasospastic cor...

Tang(H),Sun(Z),Wang(S),Chen(Z),Wang(W),Wan... Front Cardiovasc Med None

...PIK3CA, NOS3, PPARG, TNF, and RELA). DSG demonstrated significant cardioprotective effects in vasospastic CHD rats, whic...

Elucidation of the Material Basis of Yiqi Qingjie Formula Against IgA Nephrop...

Lin(L),Zhou(S),Li(J),Li(H),Zhang(Q),Cui(H)... J Vis Exp 2026-05-19

...PIK3CA) and three major blood-absorbed compounds-Deacetylasperulosidic acid, Geniposidic acid, and Dioscin -with consist...

Integrating Network Pharmacology and Molecular Docking to Investigate the Act...

Chen(Z),Xiao(X),Zhao(Y),Li(Y),Wang(C),Zhao... Curr Pharm Des 2026-06-08

...PIK3CA. Molecular docking further validated potential binding of these compounds to inflammatory targets IL-6 and IL-1B,...

New perspectives on endocrine therapy suitability for hormone receptor-positi...

Rugo(HS),Curigliano(G),Cescon(DW),Penault-... Breast 2026-08-00

...PIK3CA), and visceral disease, are currently used to guide treatment decisions. However, international guidelines have v...

Pharmacologic Features, Clinical Applications, and Drug Safety Evaluation of ...

Di Lauro(V),Rizzo(A),Sacco(PC),Palma(V),Ci... Clin Breast Cancer 2026-07-00

...PIK3CA mutations are found in around 40% of cases and are associated with a poor prognosis. In BCs with alterations in t...

Human stem cell models in cerebral cavernous malformations.

Wang(Q),Sun(J),Zhu(X),Yu(T),Xiao(X) Stem Cell Res Ther 2026-06-09

...PIK3CA disrupt endothelial homeostasis in both two-dimensional and three-dimensional contexts, leading to aberrant activ...

Exosomal miR-27a-5p Helps Differentiate Parathyroid Carcinoma From Adenoma an...

Wang(J),Wang(Y),Wang(Q),Zhao(T),Shen(H),Li... Int J Endocrinol None

...PIK3CA, was identified using a dual-luciferase assay. Exosomal miR-27a-5p differed significantly in PC and PA and was up...

Oncogenic PIK3CA reprograms glutamine metabolism to drive bladder cancer prog...

Kami Reddy(KR),Putluri(V),Piyarathna(DWB),... Cell Commun Signal 2026-07-14

...PIK3CA mutations occurring in 15-25% of cases. PIK3CA, which encodes the catalytic p110α subunit of PI3K, plays a critic...

A Real-World Study on the Effectiveness and Safety of Elacestrant in Patients...

Greco(M),Gebbia(V),Berardi(R),Usset(A),Ric... Cancers (Basel) 2026-06-24

...PIK3CA, AKT, and PTEN. The sample size was calculated according to the two-stage Simon design. Toxicity was classified a...

HER2 Alterations in Squamous Cell Lung Cancer: Biology, Therapeutic Landscape...

Elantably(D),Meerzaman(I),Hou(AY),Abdelhak... Cancers (Basel) 2026-06-30

...PIK3CA, FGFR1, SOX2, and the NFE2L2/KEAP1 oxidative stress pathway, as well as dysregulation of the NOTCH signaling path...

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