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Sexually Dimorphic RNA Helicase DDX3Y, But Not DDX3X, Plays a Potential Tumor...

Govatati(S),Malempati(S),Karnati(R),Syed(G... Biochem Genet 2026-07-11

...PIK3CA, PTEN, Snail, TCF7L1, and E-cadherin, whereas DDX3X had no significant effect on these targets. Collectively, the...

ESR1 and PIK3CA circulating tumor DNA (ctDNA) mutation status as predictive b...

Fusco(N),Malapelle(U) J Liq Biopsy 2026-09-00

...PIK3CA alterations represent different evolutionary events: PIK3CA mutations are early, clonal, and stable; ESR1 mutatio...

Integrated in silico pharmacology of Pleurotus ostreatus-derived bioactive co...

Maurya(S),Ehsan(S),Chaudhary(A),Yadav(S),S... In Silico Pharmacol None

...PIK3CA, RELA, JAK2, PTGS2, GSK3B, PIK3R1, and TLR4, which are associated with several cancer types such as breast, color...

Prognostic Role of TP53 and ARID1A Mutations in Alcohol-Consuming Patients Wi...

Adalı(Y) Appl Immunohistochem Mol Mo... 2026-07-13

...PIK3CA, or KRAS mutations. TP53 and ARID1A mutation status may have prognostic relevance among alcohol-consuming patient...

Osimertinib Plus Gefitinib in Patients with EGFR-Mutated Advanced Non-Small C...

Goldberg(SB),Ahn(MJ),Baik(C),De Castro Car... Clin Cancer Res 2026-07-13

...PIK3CA mutations) were identified following PD on osimertinib-gefitinib. Osimertinib-gefitinib demonstrated modest clini...

Genomic landscape and therapeutic implications of Anaplastic Lymphoma Kinase ...

Li(X),Yasin(F),Pavlick(DC),Ross(JS),Cecchi... Oncologist 2026-08-06

...PIK3CA mutations. ALK fusions define a rare but biologically distinct subset of CRC characterized by frequent MSI-high/M...

Associations of Age With Tumor Genomic Characteristics in Relapsed/Refractory...

Sankaran(H),Kotliarov(Y),Zhao(Y),Harris(LN... JCO Precis Oncol 2026-08-00

...PIK3CA (1.1 [1.1 to 1.2]), breast cancer; and BRAF (1.4 [1.2 to 1.7]), female colorectal cancer. Associations with young...

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head &...

Taqvi(A),Huynh(TK),Kadam(A),Kardan(Z),Yan(... Mol Oncol 2026-08-07

...PIK3CA, NOTCH1, and TP53 among others that contribute to tumorigenesis. In this study, we focused on somatostatin recept...

Oncogenic PIK3CA enhances collective migration of mammary epithelial cells th...

Dayoub(A),Fokin(AI),Leonov(S),Gautreau(AM)... J Cell Sci 2026-08-01

Oncogenic mutations of the PIK3CA gene, which encodes the catalytic subunit of the phosphatidylinositol 3-kinase (PI3K) ...

Insulin receptor substrate 2 (IRS2) confers resistance to PI3K pathway inhibi...

Lero(MW),Morgan(JS),Card(MA),Zhu(LJ),Li(J)... J Biol Chem 2026-08-10

...PIK3CA mutant breast tumors and cell lines, there is a significant reduction in IRS2 mRNA and protein abundance which is...

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