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Molecular Profiling of Urothelial Bladder Cancer: Bridging Tumor Biology and ...

Thibault(C),Blons(H),Allory(Y),Harba(A),Ro... Eur Urol Oncol 2026-07-08

...PIK3CA mutations, loss of chromosome 9, and widespread chromatin-remodeling gene alterations. MIBC displays high genomic...

Addition of angiogenesis inhibitors to CDK4/6 inhibitors and fulvestrant in h...

Zhang(M),Niu(L),Lyu(H),Liu(Z),Zeng(H),Lu(Z... Chin Med J (Engl) 2026-07-07

...PIK3CA and BRCA1/2. Based on dose-limiting toxicities and preliminary efficacy, daily famitinib 10 mg combined with dalp...

Systematic Investigation of Key Drivers of Lung Adenocarcinoma: A Focus on Ge...

Navaei(M),Karami(F),Jahanimoghadam(A),Zare... Cancer Invest 2026-07-09

...PIK3CA, BRAF, EGFR, ERBB2, FGFR3, MTOR, and TP53, along with KRAS, MET, and FGFR2, emerged as potential biomarkers. Addi...

T-cell lymphoma of the breast and ovary presenting as a second malignant neop...

Alvarez-Palacios(O),Ojeda-Campos(L),Rodríg... Rare Tumors None

...PIK3CA). The disease progressed rapidly despite CHOP chemotherapy, and the patient died shortly after diagnosis. This re...

Metastatic extramammary Paget's disease successfully treated by trastuzumab d...

Chou(LP),Lee(MY),Fang(CL),Tung(CL),Lin(IL)... Front Med (Lausanne) None

...PIK3CA, and PTEN mutations. Initially, he received trastuzumab and pembrolizumab. However, there was no clinical respons...

Yizhi Dihuang Decoction Ameliorates Mild Cognitive Impairment by Restoring Au...

Hao(Z),Meng(T),Li(S),Bu(Y),Qie(R),Chen(J) Rejuvenation Res 2026-07-09

...PIK3CA, PIK3CD, and mTOR; docking supported feasible engagement. In vivo, YZDHD improved spatial learning and recognitio...

PFKP promotes oncogenesis in osteosarcoma through PI3K/HIF-1α pathway-mediate...

Zhang(X),Guan(M),Wang(Y),Ding(C),Yu(X),Shi... Cell Signal 2026-11-00

...PIK3CA and HIF1A. Furthermore, through analysis of the HERB and CTD databases and molecular docking simulations, we unco...

Somatic Mutation Profiles in Colorectal Cancers Differ by Population.

Mabvakure(BM),Promprasert(P),Martinez Cruz... medRxiv 2026-06-29

...PIK3CA, and TP53 , as well as in pathogenic variant occurrence. Geographic origin and age of onset appear to shape the C...

Beyond Lesion Control: A Narrative Review of Targeted Therapy and Surgical De...

Altamimi(O),Altamimi(I),Alhowidi(R),Alosai... Cureus 2026-06-00

...PIK3CA-related overgrowth spectrum and selected vascular malformations, has shifted the management paradigm. These agent...

Endophytic Aspergillus glaucus as a novel epothilone B producer: Antiprolifer...

El-Sayed(ASA),Refaat(S),El-Sayed(MA),Fikry... Appl Microbiol Biotechnol 2026-07-10

...PIK3CA, mTOR, and HSP90, in addition to binding the β-tubulin taxane site, highlighting its capacity to modulate multipl...

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