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HER3 Expression and PIK3CA Mutational Status Predict Pathological Response of...

Xia(X),Zong(Z),Shen(J),Zhou(L),Lei(Y),Li(J... Cancer Res Treat 2026-07-00

...PIK3CA mutation for the efficacy of neoadjuvant therapy in human epidermal growth factor receptor 2 (HER2)-positive brea...

Tumor Genomic Profiles Associated with Clinical Benefit from Immune Checkpoin...

Potthoff(K),Vannier(C),Martens(UM),Matter(... Onco Targets Ther None

...PIK3CA and MRE11. Our analysis revealed a set of three genes (KEAP1, PIK3CA and MRE11) exclusively mutated in patients w...

The Molecular and Immunological Landscape in Nasopharyngeal Carcinoma (NPC) D...

Bracken-Clarke(D),Xue(E),Krause(H),Adeyelu... Cancer Med 2026-09-00

...PIK3CA (20.51%) and CYLD (10.53%)/NFKBIA (12.82%) mutations were enriched in SSTR2-Q1 versus -Q4. Tumor mutation burden ...

Oncogenic Signalling and Immune Checkpoint Crosstalk in Cancer: Emerging Targ...

Sekar(PKC),Veerabathiran(R) Curr Drug Targets 2026-08-18

...PIK3CA mutation, and AI-guided modelling frameworks offer structured approaches for translating these findings into clin...

Recurrent PIK3CA-E545K mutation promotes cervical cancer growth and invasion ...

Huang(C),Zhang(W),Ma(X),Li(X),Sun(X) Mol Genet Genomics 2026-08-07

...PIK3CA as one of the most frequently mutated genes in cervical cancer. Functional analyses demonstrated that PIK3CA E545...

PIK3CA silencing restores anoikis sensitivity in endothelial cells.

Pereira(DMC),de Sousa Mesquita(AP),da Silv... Mol Biol Rep 2026-08-29

...PIK3CA gene silencing in anoikis-resistant endothelial cells. Consequently, these cells exhibited a reversal of malignan...

Fetal magnetic resonance imaging features of syndromic megalencephaly: a syst...

Libzon(S),Hausman-Kedem(M),Waiserberg(N),B... Pediatr Radiol 2026-08-18

...PIK3CA-AKT-mTOR pathway and hemimegalencephaly, and between RASopathies and enlarged extra-axial spaces. Current evidenc...

GLSP ameliorates monocrotaline-induced pulmonary arterial hypertension throug...

Wei(Y),Zuo(S),Deng(N),Guo(H),You(L),Zuo(Y)... J Mol Histol 2026-08-18

...PIK3CA, HSP90AA1, and ESR1-key nodes within these pathways. Our findings, from both in vivo and in vitro experiments, de...

Integrated Analysis of the STING1-IRF1 Signaling Pathway and Genomic Alterati...

Alhamadani(I),Alzeyadi(M) Asian Pac J Cancer Prev 2026-08-01

...PIK3CA (53%), TP53 (46%) genes in addition to mutations in STING1which was directly linked to a disruption in tumor sign...

LC-MS/MS-based metabolomics analysis and experimental verification reveal the...

Feng(C),Yang(C),Gao(W),Liu(Y),Wei(J),Shen(... Naunyn Schmiedebergs Arch P... 2026-05-00

...PIK3CA and p-PI3K and p-AKT. The results of cellular metabolomics analysis indicate that the drug-containing serum can r...

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