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Association of genomic driver mutation, histologic subtype, and mTORC1 biomar...

Bhardwaj(S),Amaral(A),Dairo(O),Akbari(A),P... Hum Pathol 2026-09-00

...PIK3CA alterations (p = 0.02) with a nonsignificant trend for p-S6 (p = 0.15). There was no significant association of G...

Integrative analysis of Trichosanthes kirilowii maxim formula granules' anti-...

Gao(Y),Lu(Y),Liu(Y),Liu(F),Zhang(J),Xu(F),... Front Pharmacol None

...PIK3CA, BCL2L1, and CDC42. The compound-target-pathway-disease network showed that schisandrin binds to many treatment t...

Long-Read Haplotype Phasing Resolves Allelic Configuration as a Missing Layer...

Vo(JN),Wu(YM),Wang(R),Pham(T),Cao(X),Yeung... medRxiv 2026-05-05

...PIK3CA, PDGFRB, and KIT with functionally synergistic activity. Haplotype phasing resolves a systematically overlooked g...

Natural Product Toosendanin Suppresses the Malignant Development of Skin Mela...

Dai(H),Zhang(XM),Zhang(JC),Deng(XT),Liu(Q)... Adv Sci (Weinh) 2026-08-30

...PIK3CA transcription in melanoma cells. In clinical samples and melanoma datasets, BNC2 expression is substantially elev...

A marine-derived meroterpenoid inhibits colorectal cancer via PI3K pathway mo...

Han(MQ),Zhang(JC),Zhao(YJ),Liu(YF),Zhu(HJ)... Mar Life Sci Technol 2026-08-00

...PIK3CA or aberrant AKT signaling in approximately 30%-40% of cases. Marine natural products, especially those derived fr...

Implementing liquid biopsy in HR+/HER2- metastatic breast cancer: challenges ...

Frescura(V),Cristofanilli(M),Reduzzi(C),Po... Curr Opin Oncol 2026-09-03

...PIK3CA - achieved regulatory validation as a primary predictive biomarker for treatment selection, supporting the approv...

Lynch syndrome-associated urothelial carcinoma: clinical and molecular findin...

Rametta(A),Barella(M),Scardino(A),Barbetta... Fam Cancer 2026-09-02

...PIK3CA, which co-occurred with FGFR3 p.Arg248Cys. No gene fusions were identified. This study expands the limited molecu...

Clinical and biological characteristics associated with loss-of-heterozygosit...

Blanc-Durand(F),Rouleau(E),Pautier(P),Ngoi... J Gynecol Oncol 2026-01-00

...PIK3CA, CTNNB1, and PTEN mutations. The median overall survival was 42.2, 55.2, and 100.8 months in the LOH-high, interm...

Inavolisib for PIK3CA-mutated advanced endometrial cancer: a multicentric, ph...

Passarelli(A),Bartoletti(M),Farolfi(A),Iac... Int J Gynecol Cancer 2026-08-09

...PIK3CA mutation will receive inavolisib. Patients aged 18 years and older with documented evidence of PIK3CA mutated adv...

Primary mucoepidermoid carcinoma of the liver: Clinicopathological features, ...

Zhu(Y),Shao(Y),Guo(J),Lin(W),Deng(J),Pan(Y... Cancer Treat Res Commun 2026-09-05

...PIK3CA, CDK4, MDM2 and MYC were found in another case. The clinicopathological features and mutational profiles of MEC-L...

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