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Clinical and molecular features of resected breast cancer brain metastases: a...

Krasnow(NA),Salans(M),Jayaraj(M),Kuwahara(... Breast Cancer Res Treat 2026-07-20

...PIK3CA mutation (n = 9, 22.5%); 31 patients (77.5%) had therapeutically targetable mutations. mrwOS from BM resection wa...

Screening the effective components of Ficus tikoua on the treatment of lipopo...

Li(M),Xu(Y),Yang(M),Jiang(X),Liu(Y),Lei(L)... J Pharm Biomed Anal 2026-12-15

...PIK3CA, PIK3CB, and PIK3CD). Experimental validation further revealed that FTE inhibited PI3K/AKT overactivation, as evi...

Adjuvant aspirin for colorectal cancer with PIK3CA-mutated and COX-2 overexpr...

Segelov(E),Li(S),Li(I),Mouradov(D),Yip(S),... EBioMedicine 2026-08-00

...PIK3CA and PTEN in 289 tumours and by Sanger sequencing for PIK3CA exon 9 or 20 (9/20) mutations in a further 108. PTGS2...

MDM4 Amplification in Liposarcoma: A Rare Finding or an Underrecognized Pathway?

Carilla Sanromán(A),Ligorred(L),Ollero Dom... Int J Surg Pathol 2026-07-21

...PIK3CA and TERT. This finding supports MDM4 as a potential alternative driver in liposarcomagenesis, possibly correlatin...

WIN-MTB-2024017 - WIN International Molecular Tumor Board: A 48-year-old fema...

El-Deiry(WS),Hernando-Calvo(A),Dizon(D),Ma... Oncotarget 2026-07-21

...PIK3CA mutations; therapies targeting PIK3CA and EGFR alterations; regular imaging and liquid biopsies assessments for m...

Dynamic Changes in Circulating and Tissue Biomarkers and Therapeutic Response...

Shi(Y),Zhang(J),Gu(J),Zhao(W),Li(G),He(X) Digestion 2026-07-21

...PIK3CA, MYC, and FGFR2 were detected in ctDNA and were associated with shorter progression-free survival. CD8+ T-cell in...

Eribulin versus taxane as first-line chemotherapy combined with dual HER2 blo...

Saji(S),Yamashita(T),Tsurutani(J),Sagara(Y... ESMO Open 2026-08-00

...PIK3CA mutations (PIK3CAm+; E542K, E545K, H1047R, and N345K single nucleotide variants) or HER2 amplification (HER2 amp+...

Apocrine encapsulated papillary carcinoma of the breast with microscopic mult...

Wang(J),Lu(M),Jiang(L) Front Oncol None

...PIK3CA exon 20 H1047R/L hotspot mutation was detected. After multidisciplinary discussion, no systemic therapy was admin...

High frequency of RB1 mutations p16 positive early stage oropharyngeal carcin...

Brown(MH),Mendes(WS),Song(Y),Shetty(AC),Wi... Oral Oncol 2026-08-00

...PIK3CA, RB1, FBXW7, FGFR3, TP53, CYLD, B2M, FLCN, FGF23, and ERBB2. Compared to reported rates in predominantly advanced...

Endometriosis and ovarian cancer: epidemiological evidence, molecular insight...

Leone Roberti Maggiore(U),Vignali(M),Kvask... Hum Reprod Update 2026-05-17

...PIK3CA, and KRAS are shared between endometriosis and certain OC subtypes, and the nature of the environment typical of ...

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