Kerami(Z),Duijvis(NW),Vogels(EW),van Dooren(… J Crohns Colitis 2014-10-00

...NFKBIZ, CXCL1, and CXCL6 demonstrated the most prominent response. qRT-PCR validated that IL-17 induced the expression o...

Tsoi(Lam C),Spain(Sarah L),Ellinghaus(Eva),S… Nat Commun 2016-02-29

...NFKBIZ (3q12.3) and CAMK2G (10q22.2). We further demonstrate that NFKBIZ is a TRAF3IP2-dependent target of IL-17 signall...

Taylor(TC),Coleman(BM),Arunkumar(SP),Dey(I),… Cell Host Microbe 2023-00-11

...Nfkbiz, a non-canonical NF-κB transcription factor) was upregulated in an interleukin (IL)-17-dependent manner and was e...

Zhang(R),Kan(Y),Liu(H),Pan(P),Hu(X),Xu(Y),Wa… Cell Immunol 2026-04-00

...NFKBIZ, TNFAIP2, and CTSS. Single-cell analysis demonstrated distinct expression of these hub genes in immunosuppressive...

Ovesen(SK),Schulze-Osthoff(K),Iversen(L),Joh… Acta Derm Venereol 2021-02-09

...NFKBIZ, was identified as a key regulator required for TNFα/IL-17A-induced IL-36γ expression. TNFα/IL-17A-induced IL-36γ...

Slowikowski(K),Nguyen(HN),Noss(EH),Simmons(D… Proc Natl Acad Sci U S A 2020-00-10

...NFKBIZ). In the promoters of CXCL1, CXCL2, and CXCL3, we found a putative CUX1-NF-κB binding motif not found elsewhere i...

Pan(X),Liao(B),Hu(Z),Xiong(Y) Biology (Basel) 2026-01-02

...NFKBIZ+ M0 macrophage subset predominantly present in non-responders. Notably, these macrophages exhibit a hypoxia-induc...

Zhang(J),Chen(Y),Lin(Z),Xu(C),Zhu(L),Zhang(C) ACS Appl Bio Mater 2026-02-02

...NFKBIZ siRNA (siNFKBIZ) into nanoparticles, followed by surface modification with liposomes. This design simultaneously ...

Xie(M),Wu(Y),Zhang(Y),Lu(R),Zhai(Z),Huang(Y)… Adv Mater 2024-08-00

...NFKBIZ siRNAs with corneal epithelium cell (CEC)-derived exosomes to form a HEV construct for the treatment of dry eye d...

Taki(N),Kimura(A),Shiraishi(Y),Maruyama(T),O… J Orthop Sci 2025-03-00

Transcription factor protein IκBζ (encoded by the Nfkbiz gene) regulates nuclear factor-κB (NF-κB) and is involved in th...