...BRCA1 and BRCA2, can be specifically killed by inhibitors of the base excision repair enzyme, poly(ADP-ribose) polymeras...
...BRCA1-associated protein 1 (BAP1) deficiency strongly correlates with UM metastasis, its mechanistic role remains unclea...
...BRCA1, and ATF5, which might be potential therapeutic targets. Cell-cell communication analysis demonstrated that hyperm...
...BRCA1/2, TP53, PALB2, CHEK2, and EGFR. Prevalence rates varied by gene, cohort characteristics, ethnicity, and histology...
Pathogenic coding variants in BRCA1, BRCA2 and PALB2 confer hereditary breast/ovarian cancer risk, yet these regions com...
...BRCA1/2 and mutations in PALB2 were associated with high HRD scores (≥42). Notably, a subset of patients without germlin...
...BRCA1 and BRCA2 and is associated with the BRCA2-dependent accumulation of RAD51 recombinase in chromatin. Our data iden...
...BRCA1/2, the therapeutic implications of BRCA1-associated protein 1 (BAP1) alterations are unclear. We describe three pa...
...BRCA1/2, and other DNA repair genes are more prevalent, along with basal-like intrinsic subtypes that exhibit high proli...
...BRCA1-associated RING domain 1) in newly diagnosed multiple myeloma (NDMM), which has not been well defined previously. ...
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